Clinical Outcomes of Ruxolitinib Treatment in Patients With IPSS Intermediate-1-Risk Myelofibrosis: Interim Analysis From an Italian, Prospective Study (ROMEI).
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| Title: | Clinical Outcomes of Ruxolitinib Treatment in Patients With IPSS Intermediate-1-Risk Myelofibrosis: Interim Analysis From an Italian, Prospective Study (ROMEI). |
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| Authors: | Guglielmelli P; Department of Experimental and Clinical Medicine, CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, University of Florence, Florence, Italy., Breccia M; Hematology, Department of Translational and Precision Medicine, Azienda Policlinico Umberto I, Sapienza University, Rome, Italy., Mendicino F; A. O. di Cosenza, Presidio Ospedaliero Annunziata, Cosenza, Italy., Martelli M; A. O. Policlinico Umberto I, Università La Sapienza, Roma, Italy., Di Renzo N; Hematology and Hematopoietic Stem Cell Transplantation Unit. PO 'Vito Fazzi'. ASL Lecce, Lecce, Italy., Palumbo GA; Department of Scienze Mediche, Chirurgiche e Tecnologie Avanzate 'G.F. Ingrassia', University of Catania, Catania, Italy., Crugnola M; Hematology Unit, University Hospital of Parma, Parma, Italy., Musso M; Ospedale La Maddalena, Palermo, Italy., Sibilla S; Unit of Hematology and Hemopoietic Stem Cell Transplantation, Ospedale Cardinale G Panico, Tricase, Italy., Sportoletti P; Institute of Hematology-Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy., Abruzzese E; Hematology, S. Eugenio Hopsital, ASL Roma 2, Tor Vergata University, Rome, Italy., Impera S; U.O.C. Ematologia, A. O.ad Alta Specializzazione Ospedale Garibaldi Nesima, Catania, Italy., Malato A; A.O. Ospedali Riuniti Villa Sofia-Cervello - P.O. Cervello, Palermo, Italy., Siragusa S; Az. Osp. Univ. Policlinico P Giaccone Università degli Studi Palermo, Palermo, Italy., Selleri C; Hematology and Bone Marrow Unit, AOU S.Giovanni di Dio e Ruggi d'Aragona, Department of Medicine and Surgery, University of Salerno, Fisciano, Italy., Pane F; A. O. U. Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy., Martino B; A.O. Bianchi Melacrino Morelli - Presidio Ospedali Riuniti, Reggio di Calabria, Italy., Ricco A; Az. Osp. Univ. Consorziale Policlinico di Bari Università degli Studi, Bari, Italy., Gardellini A; Division of Hematology, Valduce Hospital, Como, Italy., Liberati AM; S.C. Oncoematologia Azienda Ospedaliera S Maria di Terni, Terni, Italy., Tafuri A; Hematology, Department of Clinical and Molecular Medicine, University Hospital Sant'Andrea-Sapienza, Rome, Italy., Langella M; Presidio Ospedaliero Andrea Tortora - ASL Salerno, Pagani, Italy., Brociner M; ASST Sette Laghi Osp. di Circolo e Fond Macchi, Varese, Italy., Ditonno P; IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy., Pastore D; UOC Ematologia e Trapianto di Midollo, Presidio Osp. A. Perrino ASL BR, Brindisi, Italy., Mulas O; A. O. Brotzu Osp. Onc. Armando Businco Centro Rif Onc. Reg, Cagliari, Italy., Pocali B; Dip. Pneumo-Oncoematologico, Azienda Ospedaliera di Rilievo Nazionale A. Cardarelli, Napoli, Italy., De Gobbi M; Department Clinical and Biological Sciences University of Torino, A.O.U. S. Luigi Gonzaga Orbassano, Turin, Italy., Morsia E; Department of Hematology, A.O.U. Ospedali Riuniti di Ancona Presidio Umberto I, Ancona, Italy., Benevolo G; Hematology U., A.O.U. Città della Salute e della Scienza, Turin, Italy., Elli EM; Hematology Division and Bone Marrow Unit, Fondazione IRCCS, San Gerardo dei Tintori, Monza, Italy., De Stefano V; Section of Hematology, Catholic University, Fondazione Policlinico A. Gemelli IRCCS, Roma, Italy., Falcone AP; Division of Hematology IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., Vallisa D; Hematology and Bone Marrow Transplant Unit, Presidio Ospedaliero di Piacenza AUSL, Piacenza, Italy., Tomassetti S; Hematology Unit, Infermi Hospital Rimini, Rimini, Italy., Lunghi F; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Hospital, Milan, Italy., Orofino N; Division of Hematology, Legnano's Hospital, Milan, Italy., Carli G; Presidio Ospedaliero S. Bortolo ULSS 6 Vicenza, Vicenza, Italy., Urbano T; Hematology Ospedale San Giuseppe Moscati, Taranto, Italy., Lucchesi A; IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Brunoventre M; U.O. Oncologia Medica, ASST Fatebenefratelli Sacco Ospedale Fatebenefratelli Oftalmico, Milano, Italy., Bonifacio M; Department of Engineering for Innovation Medicine, Section of Innovation Biomedicine, University of Verona, Verona, Italy., Binotto G; Department of Medicine, Hematology Unit, Padova University Hospital, Padova, Italy., Cavazzini F; Az. Osp. Univ. Ferrara Arcispedale S Anna Univ. degli Studi, Ferrara, Italy., Ranalli P; Department of Medicine and Aging Sciences, 'G. D'Annunzio' University, Chieti, Italy.; Hematology Unit, Department of Oncology and Hematology, Ospedale Civile 'Santo Spirito', Pescara, Italy., Allegra A; Az. Ospe.Universitaria Policlinico G. Martino Univ. di, Messina, Italy., Anaclerico B; Azienda Ospedaliera S Giovanni Addolorata, Rome, Italy., Mazzotta S; Division of Hematology, Ospedale 'C. e G. Mazzoni', ASUR Marche-AV5, Ascoli Piceno, Italy., Gherlinzoni F; Pres.Ospedaliero S. Maria di Ca' Foncello, Treviso, Italy., Tiribelli M; Division of Hematology and BMT, ASUFC and Department of Medicine, University of Udine, Udine, Italy., Castiglioni C; Novartis Farma S.P.A., Milano, Italy., Landoni M; Novartis Farma S.P.A., Milano, Italy., Valsecchi D; Novartis Farma S.P.A., Milano, Italy., Magnoli M; OPIS s.r.l., Desio, Italy., Passamonti F; Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Palandri F; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia 'Seràgnoli', Bologna, Italy. |
| Source: | Hematological oncology [Hematol Oncol] 2026 Mar; Vol. 44 (2), pp. e70178. |
| Publication Type: | Journal Article; Multicenter Study; Observational Study |
| Journal Info: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8307268 Publication Model: Print Cited Medium: Internet ISSN: 1099-1069 (Electronic) Linking ISSN: 02780232 NLM ISO Abbreviation: Hematol Oncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41877599 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Clinical Outcomes of Ruxolitinib Treatment in Patients With IPSS Intermediate-1-Risk Myelofibrosis: Interim Analysis From an Italian, Prospective Study (ROMEI). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Guglielmelli+P%22">Guglielmelli P</searchLink>; Department of Experimental and Clinical Medicine, CRIMM, Center for Research and Innovation of Myeloproliferative Neoplasms, AOU Careggi, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Breccia+M%22">Breccia M</searchLink>; Hematology, Department of Translational and Precision Medicine, Azienda Policlinico Umberto I, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mendicino+F%22">Mendicino F</searchLink>; A. O. di Cosenza, Presidio Ospedaliero Annunziata, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Martelli+M%22">Martelli M</searchLink>; A. O. Policlinico Umberto I, Università La Sapienza, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Renzo+N%22">Di Renzo N</searchLink>; Hematology and Hematopoietic Stem Cell Transplantation Unit. PO 'Vito Fazzi'. ASL Lecce, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Palumbo+GA%22">Palumbo GA</searchLink>; Department of Scienze Mediche, Chirurgiche e Tecnologie Avanzate 'G.F. Ingrassia', University of Catania, Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Crugnola+M%22">Crugnola M</searchLink>; Hematology Unit, University Hospital of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Musso+M%22">Musso M</searchLink>; Ospedale La Maddalena, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Sibilla+S%22">Sibilla S</searchLink>; Unit of Hematology and Hemopoietic Stem Cell Transplantation, Ospedale Cardinale G Panico, Tricase, Italy.<br /><searchLink fieldCode="AU" term="%22Sportoletti+P%22">Sportoletti P</searchLink>; Institute of Hematology-Centro di Ricerche Emato-Oncologiche (CREO), University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Abruzzese+E%22">Abruzzese E</searchLink>; Hematology, S. Eugenio Hopsital, ASL Roma 2, Tor Vergata University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Impera+S%22">Impera S</searchLink>; U.O.C. Ematologia, A. O.ad Alta Specializzazione Ospedale Garibaldi Nesima, Catania, Italy.<br /><searchLink fieldCode="AU" term="%22Malato+A%22">Malato A</searchLink>; A.O. Ospedali Riuniti Villa Sofia-Cervello - P.O. Cervello, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Siragusa+S%22">Siragusa S</searchLink>; Az. Osp. Univ. Policlinico P Giaccone Università degli Studi Palermo, Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Selleri+C%22">Selleri C</searchLink>; Hematology and Bone Marrow Unit, AOU S.Giovanni di Dio e Ruggi d'Aragona, Department of Medicine and Surgery, University of Salerno, Fisciano, Italy.<br /><searchLink fieldCode="AU" term="%22Pane+F%22">Pane F</searchLink>; A. O. U. Università degli Studi della Campania Luigi Vanvitelli, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Martino+B%22">Martino B</searchLink>; A.O. Bianchi Melacrino Morelli - Presidio Ospedali Riuniti, Reggio di Calabria, Italy.<br /><searchLink fieldCode="AU" term="%22Ricco+A%22">Ricco A</searchLink>; Az. Osp. Univ. Consorziale Policlinico di Bari Università degli Studi, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Gardellini+A%22">Gardellini A</searchLink>; Division of Hematology, Valduce Hospital, Como, Italy.<br /><searchLink fieldCode="AU" term="%22Liberati+AM%22">Liberati AM</searchLink>; S.C. Oncoematologia Azienda Ospedaliera S Maria di Terni, Terni, Italy.<br /><searchLink fieldCode="AU" term="%22Tafuri+A%22">Tafuri A</searchLink>; Hematology, Department of Clinical and Molecular Medicine, University Hospital Sant'Andrea-Sapienza, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Langella+M%22">Langella M</searchLink>; Presidio Ospedaliero Andrea Tortora - ASL Salerno, Pagani, Italy.<br /><searchLink fieldCode="AU" term="%22Brociner+M%22">Brociner M</searchLink>; ASST Sette Laghi Osp. di Circolo e Fond Macchi, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Ditonno+P%22">Ditonno P</searchLink>; IRCCS Istituto Tumori 'Giovanni Paolo II', Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Pastore+D%22">Pastore D</searchLink>; UOC Ematologia e Trapianto di Midollo, Presidio Osp. A. Perrino ASL BR, Brindisi, Italy.<br /><searchLink fieldCode="AU" term="%22Mulas+O%22">Mulas O</searchLink>; A. O. Brotzu Osp. Onc. Armando Businco Centro Rif Onc. Reg, Cagliari, Italy.<br /><searchLink fieldCode="AU" term="%22Pocali+B%22">Pocali B</searchLink>; Dip. Pneumo-Oncoematologico, Azienda Ospedaliera di Rilievo Nazionale A. Cardarelli, Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22De+Gobbi+M%22">De Gobbi M</searchLink>; Department Clinical and Biological Sciences University of Torino, A.O.U. S. Luigi Gonzaga Orbassano, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Morsia+E%22">Morsia E</searchLink>; Department of Hematology, A.O.U. Ospedali Riuniti di Ancona Presidio Umberto I, Ancona, Italy.<br /><searchLink fieldCode="AU" term="%22Benevolo+G%22">Benevolo G</searchLink>; Hematology U., A.O.U. Città della Salute e della Scienza, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Elli+EM%22">Elli EM</searchLink>; Hematology Division and Bone Marrow Unit, Fondazione IRCCS, San Gerardo dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22De+Stefano+V%22">De Stefano V</searchLink>; Section of Hematology, Catholic University, Fondazione Policlinico A. Gemelli IRCCS, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Falcone+AP%22">Falcone AP</searchLink>; Division of Hematology IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.<br /><searchLink fieldCode="AU" term="%22Vallisa+D%22">Vallisa D</searchLink>; Hematology and Bone Marrow Transplant Unit, Presidio Ospedaliero di Piacenza AUSL, Piacenza, Italy.<br /><searchLink fieldCode="AU" term="%22Tomassetti+S%22">Tomassetti S</searchLink>; Hematology Unit, Infermi Hospital Rimini, Rimini, Italy.<br /><searchLink fieldCode="AU" term="%22Lunghi+F%22">Lunghi F</searchLink>; Unit of Hematology and Bone Marrow Transplantation, IRCCS San Raffaele Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Orofino+N%22">Orofino N</searchLink>; Division of Hematology, Legnano's Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Carli+G%22">Carli G</searchLink>; Presidio Ospedaliero S. Bortolo ULSS 6 Vicenza, Vicenza, Italy.<br /><searchLink fieldCode="AU" term="%22Urbano+T%22">Urbano T</searchLink>; Hematology Ospedale San Giuseppe Moscati, Taranto, Italy.<br /><searchLink fieldCode="AU" term="%22Lucchesi+A%22">Lucchesi A</searchLink>; IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Brunoventre+M%22">Brunoventre M</searchLink>; U.O. Oncologia Medica, ASST Fatebenefratelli Sacco Ospedale Fatebenefratelli Oftalmico, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Bonifacio+M%22">Bonifacio M</searchLink>; Department of Engineering for Innovation Medicine, Section of Innovation Biomedicine, University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Binotto+G%22">Binotto G</searchLink>; Department of Medicine, Hematology Unit, Padova University Hospital, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Cavazzini+F%22">Cavazzini F</searchLink>; Az. Osp. Univ. Ferrara Arcispedale S Anna Univ. degli Studi, Ferrara, Italy.<br /><searchLink fieldCode="AU" term="%22Ranalli+P%22">Ranalli P</searchLink>; Department of Medicine and Aging Sciences, 'G. D'Annunzio' University, Chieti, Italy.; Hematology Unit, Department of Oncology and Hematology, Ospedale Civile 'Santo Spirito', Pescara, Italy.<br /><searchLink fieldCode="AU" term="%22Allegra+A%22">Allegra A</searchLink>; Az. Ospe.Universitaria Policlinico G. Martino Univ. di, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Anaclerico+B%22">Anaclerico B</searchLink>; Azienda Ospedaliera S Giovanni Addolorata, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzotta+S%22">Mazzotta S</searchLink>; Division of Hematology, Ospedale 'C. e G. Mazzoni', ASUR Marche-AV5, Ascoli Piceno, Italy.<br /><searchLink fieldCode="AU" term="%22Gherlinzoni+F%22">Gherlinzoni F</searchLink>; Pres.Ospedaliero S. Maria di Ca' Foncello, Treviso, Italy.<br /><searchLink fieldCode="AU" term="%22Tiribelli+M%22">Tiribelli M</searchLink>; Division of Hematology and BMT, ASUFC and Department of Medicine, University of Udine, Udine, Italy.<br /><searchLink fieldCode="AU" term="%22Castiglioni+C%22">Castiglioni C</searchLink>; Novartis Farma S.P.A., Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Landoni+M%22">Landoni M</searchLink>; Novartis Farma S.P.A., Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Valsecchi+D%22">Valsecchi D</searchLink>; Novartis Farma S.P.A., Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Magnoli+M%22">Magnoli M</searchLink>; OPIS s.r.l., Desio, Italy.<br /><searchLink fieldCode="AU" term="%22Passamonti+F%22">Passamonti F</searchLink>; Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Palandri+F%22">Palandri F</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia 'Seràgnoli', Bologna, Italy. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228307268%22">Hematological oncology</searchLink> [Hematol Oncol] 2026 Mar; Vol. 44 (2), pp. e70178. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Observational Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8307268 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1099-1069 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202780232%22">02780232 </searchLink><i>NLM ISO Abbreviation: </i>Hematol Oncol <i>Subsets: </i>MEDLINE |
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