Binge drinking, metabolic dysfunction, and the spectrum of steatotic liver disease in the USA: a cross-sectional and longitudinal analysis.
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| Title: | Binge drinking, metabolic dysfunction, and the spectrum of steatotic liver disease in the USA: a cross-sectional and longitudinal analysis. |
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| Authors: | Younossi ZM; The Global NASH/MASH and Liver Councils, Washington, DC, USA; The Global Center for Liver Outcomes & Policy Research (G-CLORP), Georgetown University School of Medicine, Washington, DC, USA. Electronic address: zobair.younossi@cldq.org., Krag A; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Center for Liver Research, Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark., Zelber-Sagi S; The Global NASH/MASH and Liver Councils, Washington, DC, USA; School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel., Kalligeros M; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Arrese M; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Departamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile., Diaz LA; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Departamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile., Arab JP; Departamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile; Stravitz-Sanyal Institute for Liver Disease and Metabolic Health, Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA., Singal AK; The Global NASH/MASH and Liver Councils, Washington, DC, USA; University of Louisville School of Medicine, Louisville, KY, USA., Pessoa MG; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Departamento de Gastroenterologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Wong RJ; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Palo Alto, CA, USA., Crespo J; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Gastroenterology and Hepatology Department, Clinical and Translational Research in Digestive Diseases, Valdecilla Research Institute (IDIVAL), Marqués de Valdecilla University Hospital, Santander, Spain., Thiele M; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Center for Liver Research, Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark., Duseja A; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of Hepatology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Spearman CW; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Division of Hepatology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa., El-Kassas M; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt., Yilmaz Y; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of Gastroenterology, School of Medicine, Recep Tayyip Erdoğan University, Rize, Türkiye., Fan J; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China., Castera L; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of hepatology, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Cité, Clichy, France., Tacke F; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of Hepatology & Gastroenterology, Charité, Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany., Wong VW; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Medical Data Analytics Center, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China., Betel M; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Fatty Liver Alliance, Toronto, ON, Canada., Racila A; The Global NASH/MASH and Liver Councils, Washington, DC, USA., Nader A; The Global NASH/MASH and Liver Councils, Washington, DC, USA., Paik GY; The Global NASH/MASH and Liver Councils, Washington, DC, USA., Wajcman DI; The Global NASH/MASH and Liver Councils, Washington, DC, USA., Grinshpan LS; The Global NASH/MASH and Liver Councils, Washington, DC, USA., Henry L; The Global NASH/MASH and Liver Councils, Washington, DC, USA., Eguichi Y; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Locomedical General Institute, Locomedical Medical Cooperation, Ogi, Saga, Japan., Ong JP; The Global NASH/MASH and Liver Councils, Washington, DC, USA; College of Medicine, University of the Philippines, Manila, Philippines., Nader F; The Global NASH/MASH and Liver Councils, Washington, DC, USA., Alqahtani SA; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Liver, Digestive, and Lifestyle Health Research Section, and Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY, USA., Paik JM; The Global NASH/MASH and Liver Councils, Washington, DC, USA; The Global Center for Liver Outcomes & Policy Research (G-CLORP), Georgetown University School of Medicine, Washington, DC, USA; Center for Outcomes Research in Liver Diseases, Washington, DC, USA. |
| Source: | The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2026 Jun; Vol. 11 (6), pp. 495-508. Date of Electronic Publication: 2026 Mar 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41887238 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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Electronic address: zobair.younossi@cldq.org.<br /><searchLink fieldCode="AU" term="%22Krag+A%22">Krag A</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Center for Liver Research, Department of Gastroenterology and Hepatology, Odense University Hospital, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Zelber-Sagi+S%22">Zelber-Sagi S</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; School of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.<br /><searchLink fieldCode="AU" term="%22Kalligeros+M%22">Kalligeros M</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Arrese+M%22">Arrese M</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Departamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Diaz+LA%22">Diaz LA</searchLink>; 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The Global NASH/MASH and Liver Councils, Washington, DC, USA; Division of Hepatology, Department of Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22El-Kassas+M%22">El-Kassas M</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Endemic Medicine Department, Faculty of Medicine, Helwan University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Yilmaz+Y%22">Yilmaz Y</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of Gastroenterology, School of Medicine, Recep Tayyip Erdoğan University, Rize, Türkiye.<br /><searchLink fieldCode="AU" term="%22Fan+J%22">Fan J</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of Gastroenterology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Castera+L%22">Castera L</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of hepatology, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Cité, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Tacke+F%22">Tacke F</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Department of Hepatology & Gastroenterology, Charité, Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Wong+VW%22">Wong VW</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Medical Data Analytics Center, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Betel+M%22">Betel M</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Fatty Liver Alliance, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Racila+A%22">Racila A</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Nader+A%22">Nader A</searchLink>; 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The Global NASH/MASH and Liver Councils, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Alqahtani+SA%22">Alqahtani SA</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; Liver, Digestive, and Lifestyle Health Research Section, and Organ Transplant Center of Excellence, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Paik+JM%22">Paik JM</searchLink>; The Global NASH/MASH and Liver Councils, Washington, DC, USA; The Global Center for Liver Outcomes & Policy Research (G-CLORP), Georgetown University School of Medicine, Washington, DC, USA; Center for Outcomes Research in Liver Diseases, Washington, DC, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101690683%22">The lancet. 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