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YAP1 and QSER1 are key modulators of embryonic signaling pathways in the mammalian epiblast.

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Title: YAP1 and QSER1 are key modulators of embryonic signaling pathways in the mammalian epiblast.
Authors: Abraham E; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Roule T; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Douglas A; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Megill E; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Pericak OM; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.; Department of Neural Sciences, Center for Neural Development and Repair, Temple University, Lewis Katz School of Medicine, Philadelphia, PA, 19140, USA., Howe JE; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Choya-Foces C; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Garbincius JF; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Cohen HM; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Roig-Flórez P; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Zubillaga M; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Andrake MD; Molecular Modeling Facility, Program in Cancer Signaling and Microenvironment, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA., Kim S; Department of Neural Sciences, Center for Neural Development and Repair, Temple University, Lewis Katz School of Medicine, Philadelphia, PA, 19140, USA., Elrod JW; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA., Akizu N; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Estaras C; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA. conchi.estaras@temple.edu.; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA. conchi.estaras@temple.edu.
Source: EMBO reports [EMBO Rep] 2026 May; Vol. 27 (9), pp. 2369-2405. Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: YAP1 and QSER1 are key modulators of embryonic signaling pathways in the mammalian epiblast.
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  Data: <searchLink fieldCode="AU" term="%22Abraham+E%22">Abraham E</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Roule+T%22">Roule T</searchLink>; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Douglas+A%22">Douglas A</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Megill+E%22">Megill E</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Pericak+OM%22">Pericak OM</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.; Department of Neural Sciences, Center for Neural Development and Repair, Temple University, Lewis Katz School of Medicine, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Howe+JE%22">Howe JE</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Choya-Foces+C%22">Choya-Foces C</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Garbincius+JF%22">Garbincius JF</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Cohen+HM%22">Cohen HM</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Roig-Flórez+P%22">Roig-Flórez P</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Zubillaga+M%22">Zubillaga M</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Andrake+MD%22">Andrake MD</searchLink>; Molecular Modeling Facility, Program in Cancer Signaling and Microenvironment, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Neural Sciences, Center for Neural Development and Repair, Temple University, Lewis Katz School of Medicine, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Elrod+JW%22">Elrod JW</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA.<br /><searchLink fieldCode="AU" term="%22Akizu+N%22">Akizu N</searchLink>; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Estaras+C%22">Estaras C</searchLink>; Department of Cardiovascular Sciences, Aging + Cardiovascular Discovery Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA, 19140, USA. conchi.estaras@temple.edu.; Cancer Epigenetics Institute, Fox Chase Cancer Center, Philadelphia, PA, 19111, USA. conchi.estaras@temple.edu.
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  Data: <searchLink fieldCode="JN" term="%22100963049%22">EMBO reports</searchLink> [EMBO Rep] 2026 May; Vol. 27 (9), pp. 2369-2405. <i>Date of Electronic Publication: </i>2026 Mar 26.
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        Value: 10.1038/s44319-026-00746-z
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