Synergizing hypomethylating agents with off-the-shelf CD70-targeted chimeric antigen receptor-engineered natural killer T cells for the treatment of acute myeloid leukemia.
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| Title: | Synergizing hypomethylating agents with off-the-shelf CD70-targeted chimeric antigen receptor-engineered natural killer T cells for the treatment of acute myeloid leukemia. |
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| Authors: | Li YR; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, USA.; Department of Bioengineering, University of California, Los Angeles, CA, USA., Shen X; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, USA.; Department of Bioengineering, University of California, Los Angeles, CA, USA., Chen Y; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, USA.; Department of Bioengineering, University of California, Los Angeles, CA, USA., Zhu Y; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, USA.; Department of Bioengineering, University of California, Los Angeles, CA, USA., Huang J; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, USA.; Department of Bioengineering, University of California, Los Angeles, CA, USA., Oliai C; Division of Hematology-Oncology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA., Yang L; Department of Microbiology, Immunology & Molecular Genetics, University of California, Los Angeles, CA, USA. liliyang@ucla.edu.; Department of Bioengineering, University of California, Los Angeles, CA, USA. liliyang@ucla.edu.; Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA, USA. liliyang@ucla.edu.; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA. liliyang@ucla.edu.; Molecular Biology Institute, University of California, Los Angeles, CA, USA. liliyang@ucla.edu.; Parker Institute for Cancer Immunotherapy, University of California, Los Angeles, CA, USA. liliyang@ucla.edu.; Goodman-Luskin Microbiome Center, University of California, Los Angeles, CA, USA. liliyang@ucla.edu. |
| Source: | Leukemia [Leukemia] 2026 May; Vol. 40 (5), pp. 880-893. Date of Electronic Publication: 2026 Mar 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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