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Peripheral monocyte ratio as a predictive biomarker for metastasis-directed therapy in prostate cancer: insights from an exploratory study.

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Title: Peripheral monocyte ratio as a predictive biomarker for metastasis-directed therapy in prostate cancer: insights from an exploratory study.
Authors: Wang H; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada., Rajagopal A; Department of Medical Biophysics, University of Toronto, Toronto, Canada. Athul.rajagopal@mail.utoronto.ca.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada. Athul.rajagopal@mail.utoronto.ca., Cao K; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada., Cimolai K; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada., Petchiny TN; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., White SD; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada., Cheung J; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada., Loblaw A; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Canada., Vesprini D; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Canada., Leong H; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada., Escueta V; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada., Zhang L; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada., Glicksman R; Department of Radiation Oncology, University of Toronto, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada., Cheung P; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Canada., Wang C; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Immunology, University of Toronto, Toronto, Canada., Liu SK; Department of Medical Biophysics, University of Toronto, Toronto, Canada. Stanley.liu@utoronto.ca.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada. Stanley.liu@utoronto.ca.; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada. Stanley.liu@utoronto.ca.; Department of Radiation Oncology, University of Toronto, Toronto, Canada. Stanley.liu@utoronto.ca.
Source: BMC cancer [BMC Cancer] 2026 Mar 26; Vol. 26 (1). Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Peripheral monocyte ratio as a predictive biomarker for metastasis-directed therapy in prostate cancer: insights from an exploratory study.
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  Data: <searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.<br /><searchLink fieldCode="AU" term="%22Rajagopal+A%22">Rajagopal A</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Canada. Athul.rajagopal@mail.utoronto.ca.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada. Athul.rajagopal@mail.utoronto.ca.<br /><searchLink fieldCode="AU" term="%22Cao+K%22">Cao K</searchLink>; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.<br /><searchLink fieldCode="AU" term="%22Cimolai+K%22">Cimolai K</searchLink>; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.<br /><searchLink fieldCode="AU" term="%22Petchiny+TN%22">Petchiny TN</searchLink>; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22White+SD%22">White SD</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.<br /><searchLink fieldCode="AU" term="%22Cheung+J%22">Cheung J</searchLink>; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.<br /><searchLink fieldCode="AU" term="%22Loblaw+A%22">Loblaw A</searchLink>; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Vesprini+D%22">Vesprini D</searchLink>; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Leong+H%22">Leong H</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Canada.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.<br /><searchLink fieldCode="AU" term="%22Escueta+V%22">Escueta V</searchLink>; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.<br /><searchLink fieldCode="AU" term="%22Glicksman+R%22">Glicksman R</searchLink>; Department of Radiation Oncology, University of Toronto, Toronto, Canada.; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Cheung+P%22">Cheung P</searchLink>; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Radiation Oncology, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.; Department of Immunology, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Liu+SK%22">Liu SK</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, Canada. Stanley.liu@utoronto.ca.; Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada. Stanley.liu@utoronto.ca.; Sunnybrook Health Science Centre, Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada. Stanley.liu@utoronto.ca.; Department of Radiation Oncology, University of Toronto, Toronto, Canada. Stanley.liu@utoronto.ca.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12885-026-15854-1
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        Text: English
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