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The investigation of the inhibition effects of substituting Mg2+ with Ca2+ and Zn2+ on SARS-CoV-2 RNA-dependent RNA polymerase.

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Title: The investigation of the inhibition effects of substituting Mg2+ with Ca2+ and Zn2+ on SARS-CoV-2 RNA-dependent RNA polymerase.
Authors: Chen SH; Institute of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan., Ho Y; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan., Lin SJ; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan., Liu HL; Institute of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.
Source: Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2026 May; Vol. 44 (8), pp. 4176-4190. Date of Electronic Publication: 2026 Mar 27.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The investigation of the inhibition effects of substituting Mg<superscript>2+</superscript> with Ca<superscript>2+</superscript> and Zn<superscript>2+</superscript> on SARS-CoV-2 RNA-dependent RNA polymerase.
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  Data: <searchLink fieldCode="AU" term="%22Chen+SH%22">Chen SH</searchLink>; Institute of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+Y%22">Ho Y</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SJ%22">Lin SJ</searchLink>; School of Pharmacy, College of Pharmacy, Taipei Medical University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+HL%22">Liu HL</searchLink>; Institute of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.; Department of Chemical Engineering and Biotechnology, National Taipei University of Technology, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%228404176%22">Journal of biomolecular structure & dynamics</searchLink> [J Biomol Struct Dyn] 2026 May; Vol. 44 (8), pp. 4176-4190. <i>Date of Electronic Publication: </i>2026 Mar 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8404176 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-0254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207391102%22">07391102 </searchLink><i>NLM ISO Abbreviation: </i>J Biomol Struct Dyn <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41889305
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1080/07391102.2026.2648674
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 4176
    Titles:
      – TitleFull: The investigation of the inhibition effects of substituting Mg2+ with Ca2+ and Zn2+ on SARS-CoV-2 RNA-dependent RNA polymerase.
        Type: main
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            NameFull: Chen SH
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          Name:
            NameFull: Ho Y
      – PersonEntity:
          Name:
            NameFull: Lin SJ
      – PersonEntity:
          Name:
            NameFull: Liu HL
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          Dates:
            – D: 01
              M: 05
              Text: 2026 May
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1538-0254
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              Value: 44
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Journal of biomolecular structure & dynamics
              Type: main
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