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Gestational and lactational exposure to HIV tri-combination therapy induces sex- and dose-dependent changes in inflammatory cytokine profiles, intestinal permeability, and villi morphology in adult rat offspring.

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Title: Gestational and lactational exposure to HIV tri-combination therapy induces sex- and dose-dependent changes in inflammatory cytokine profiles, intestinal permeability, and villi morphology in adult rat offspring.
Authors: Yanamadala Y; Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States., Gokulan K; Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States., Karn K; Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States., Sutherland V; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States., Cunny H; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States., Santos JH; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States., Davis K; Toxicologic Pathology Associates, Jefferson, AR, United States., Khare S; Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 11; Vol. 17, pp. 1668334. Date of Electronic Publication: 2026 Mar 11 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Gestational and lactational exposure to HIV tri-combination therapy induces sex- and dose-dependent changes in inflammatory cytokine profiles, intestinal permeability, and villi morphology in adult rat offspring.
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  Data: <searchLink fieldCode="AU" term="%22Yanamadala+Y%22">Yanamadala Y</searchLink>; Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States.<br /><searchLink fieldCode="AU" term="%22Gokulan+K%22">Gokulan K</searchLink>; Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States.<br /><searchLink fieldCode="AU" term="%22Karn+K%22">Karn K</searchLink>; Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States.<br /><searchLink fieldCode="AU" term="%22Sutherland+V%22">Sutherland V</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States.<br /><searchLink fieldCode="AU" term="%22Cunny+H%22">Cunny H</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States.<br /><searchLink fieldCode="AU" term="%22Santos+JH%22">Santos JH</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, United States.<br /><searchLink fieldCode="AU" term="%22Davis+K%22">Davis K</searchLink>; Toxicologic Pathology Associates, Jefferson, AR, United States.<br /><searchLink fieldCode="AU" term="%22Khare+S%22">Khare S</searchLink>; Division of Microbiology, National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, United States.
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        Value: 10.3389/fimmu.2026.1668334
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      – TitleFull: Gestational and lactational exposure to HIV tri-combination therapy induces sex- and dose-dependent changes in inflammatory cytokine profiles, intestinal permeability, and villi morphology in adult rat offspring.
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              Text: 2026 Mar 11
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