Genetically diverse influenza antibodies highlight the role of IG germline gene variation and inform population-comprehensive vaccine strategies.

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Title: Genetically diverse influenza antibodies highlight the role of IG germline gene variation and inform population-comprehensive vaccine strategies.
Authors: Fischer AA; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Corcoran M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden. Electronic address: martin.corcoran@ki.se., Brouwer PJM; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Chernyshev M; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Gillespie RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Nicoletto A; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Loeffler JR; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Ferguson JA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Zygouras I; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Pushparaj P; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Rodriguez AJ; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Narang S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., van Gils MJ; Amsterdam UMC, University of Amsterdam, Department of Medical Microbiology and Infection Prevention, Amsterdam, the Netherlands., Castro Dopico X; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Kanekiyo M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA., Han J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA. Electronic address: juliannahan@scripps.edu., Karlsson Hedestam GB; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; Science for Life Laboratory, Stockholm, Sweden. Electronic address: gunilla.karlsson.hedestam@ki.se.
Source: Immunity [Immunity] 2026 Apr 14; Vol. 59 (4), pp. 1123-1139.e9. Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE
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  Data: Genetically diverse influenza antibodies highlight the role of IG germline gene variation and inform population-comprehensive vaccine strategies.
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  Data: <searchLink fieldCode="AU" term="%22Fischer+AA%22">Fischer AA</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Corcoran+M%22">Corcoran M</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden. Electronic address: martin.corcoran@ki.se.<br /><searchLink fieldCode="AU" term="%22Brouwer+PJM%22">Brouwer PJM</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chernyshev+M%22">Chernyshev M</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Gillespie+RA%22">Gillespie RA</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nicoletto+A%22">Nicoletto A</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Loeffler+JR%22">Loeffler JR</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ferguson+JA%22">Ferguson JA</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zygouras+I%22">Zygouras I</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Pushparaj+P%22">Pushparaj P</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Rodriguez+AJ%22">Rodriguez AJ</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Narang+S%22">Narang S</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22van+Gils+MJ%22">van Gils MJ</searchLink>; Amsterdam UMC, University of Amsterdam, Department of Medical Microbiology and Infection Prevention, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Castro+Dopico+X%22">Castro Dopico X</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Kanekiyo+M%22">Kanekiyo M</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, San Diego, CA, USA. Electronic address: juliannahan@scripps.edu.<br /><searchLink fieldCode="AU" term="%22Karlsson+Hedestam+GB%22">Karlsson Hedestam GB</searchLink>; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; Science for Life Laboratory, Stockholm, Sweden. Electronic address: gunilla.karlsson.hedestam@ki.se.
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  Data: <searchLink fieldCode="JN" term="%229432918%22">Immunity</searchLink> [Immunity] 2026 Apr 14; Vol. 59 (4), pp. 1123-1139.e9. <i>Date of Electronic Publication: </i>2026 Mar 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9432918 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4180 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210747613%22">10747613 </searchLink><i>NLM ISO Abbreviation: </i>Immunity <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.immuni.2026.03.002
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              Text: 2026 Apr 14
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