Elucidating the conformational dynamics of the mitochondrial localization signal, M3, of TDP-43 and accessing potential binders using molecular docking and simulation.

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Title: Elucidating the conformational dynamics of the mitochondrial localization signal, M3, of TDP-43 and accessing potential binders using molecular docking and simulation.
Authors: Balaji R; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana 502284, India., Joshi H; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana 502284, India. Electronic address: hjoshi@bt.iith.ac.in., Patel BK; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana 502284, India. Electronic address: basantkpatel@bt.iith.ac.in.
Source: Computational biology and chemistry [Comput Biol Chem] 2026 Aug; Vol. 123, pp. 109029. Date of Electronic Publication: 2026 Mar 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101157394 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-928X (Electronic) Linking ISSN: 14769271 NLM ISO Abbreviation: Comput Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Elucidating the conformational dynamics of the mitochondrial localization signal, M3, of TDP-43 and accessing potential binders using molecular docking and simulation.
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  Data: <searchLink fieldCode="AU" term="%22Balaji+R%22">Balaji R</searchLink>; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana 502284, India.<br /><searchLink fieldCode="AU" term="%22Joshi+H%22">Joshi H</searchLink>; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana 502284, India. Electronic address: hjoshi@bt.iith.ac.in.<br /><searchLink fieldCode="AU" term="%22Patel+BK%22">Patel BK</searchLink>; Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana 502284, India. Electronic address: basantkpatel@bt.iith.ac.in.
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  Data: <searchLink fieldCode="JN" term="%22101157394%22">Computational biology and chemistry</searchLink> [Comput Biol Chem] 2026 Aug; Vol. 123, pp. 109029. <i>Date of Electronic Publication: </i>2026 Mar 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101157394 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-928X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214769271%22">14769271 </searchLink><i>NLM ISO Abbreviation: </i>Comput Biol Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.compbiolchem.2026.109029
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      – TitleFull: Elucidating the conformational dynamics of the mitochondrial localization signal, M3, of TDP-43 and accessing potential binders using molecular docking and simulation.
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            NameFull: Balaji R
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              Text: 2026 Aug
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