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Familial patterns of immune dysregulation in CVID: insights from B- and T-cell phenotyping and antibody profiling.

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Title: Familial patterns of immune dysregulation in CVID: insights from B- and T-cell phenotyping and antibody profiling.
Authors: Comans SET; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands., Sprenkeler EGG; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands., Koenen MH; Department of Pediatrics, Erasmus Medical Center, Rotterdam, Netherlands., Simonetti E; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands., Van Cranenbroek B; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands., Van Rijssen E; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands., Strik-Albers R; Department of Pediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboud university medical center, Nijmegen, Netherlands., Koenen HJPM; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands., van Dongen JJM; Cytometry Service, NUCLEUS; Department of Medicine, University of Salamanca (Universidad de Salamanca), Salamanca, Spain.; Translational and Clinical Research Program, Cancer Research Center (IBMCC, CSIC - University of Salamanca), Salamanca, Spain.; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Verhagen LM; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.; Department of Pediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboud university medical center, Nijmegen, Netherlands., de Jonge MI; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands., Henriet SSV; Department of Pediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboud university medical center, Nijmegen, Netherlands.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 13; Vol. 17, pp. 1741900. Date of Electronic Publication: 2026 Mar 13 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Familial patterns of immune dysregulation in CVID: insights from B- and T-cell phenotyping and antibody profiling.
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  Data: <searchLink fieldCode="AU" term="%22Comans+SET%22">Comans SET</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sprenkeler+EGG%22">Sprenkeler EGG</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Koenen+MH%22">Koenen MH</searchLink>; Department of Pediatrics, Erasmus Medical Center, Rotterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Simonetti+E%22">Simonetti E</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Van+Cranenbroek+B%22">Van Cranenbroek B</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Van+Rijssen+E%22">Van Rijssen E</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Strik-Albers+R%22">Strik-Albers R</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Koenen+HJPM%22">Koenen HJPM</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Dongen+JJM%22">van Dongen JJM</searchLink>; Cytometry Service, NUCLEUS; Department of Medicine, University of Salamanca (Universidad de Salamanca), Salamanca, Spain.; Translational and Clinical Research Program, Cancer Research Center (IBMCC, CSIC - University of Salamanca), Salamanca, Spain.; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Verhagen+LM%22">Verhagen LM</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.; Department of Pediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Jonge+MI%22">de Jonge MI</searchLink>; Department of Laboratory Medicine, Laboratory of Medical Immunology, Radboud Community for Infectious Diseases, Radboud university medical center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Henriet+SSV%22">Henriet SSV</searchLink>; Department of Pediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboud university medical center, Nijmegen, Netherlands.
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