Structural basis of human zinc-activated channel (ZAC) signaling and modulation.

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Title: Structural basis of human zinc-activated channel (ZAC) signaling and modulation.
Authors: Zhou Z; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China., Long Y; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China., Chao Y; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China., Yang C; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China., Tang YQ; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China., Shu Y; ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, Fudan University, Shanghai, China., Zhu H; Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China. hongtao.zhu@iphy.ac.cn., Jensen AA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. aaj@sund.ku.dk., Qu Q; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China. qqh@fudan.edu.cn.
Source: Cell discovery [Cell Discov] 2026 Mar 31; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 31.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101661034 Publication Model: Electronic Cited Medium: Print ISSN: 2056-5968 (Print) Linking ISSN: 20565968 NLM ISO Abbreviation: Cell Discov Subsets: PubMed not MEDLINE
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  Data: Structural basis of human zinc-activated channel (ZAC) signaling and modulation.
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  Data: <searchLink fieldCode="AU" term="%22Zhou+Z%22">Zhou Z</searchLink>; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Long+Y%22">Long Y</searchLink>; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chao+Y%22">Chao Y</searchLink>; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink>; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Tang+YQ%22">Tang YQ</searchLink>; State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Brain Science, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Shu+Y%22">Shu Y</searchLink>; ENT Institute and Otorhinolaryngology Department of Eye & ENT Hospital, Fudan University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, China. hongtao.zhu@iphy.ac.cn.<br /><searchLink fieldCode="AU" term="%22Jensen+AA%22">Jensen AA</searchLink>; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. aaj@sund.ku.dk.<br /><searchLink fieldCode="AU" term="%22Qu+Q%22">Qu Q</searchLink>; Eye & ENT Hospital, Institutes of Biomedical Sciences, Shanghai Key Laboratory of Medical Epigenetics, International Co-laboratory of Medical Epigenetics and Metabolism (Ministry of Science and Technology), Department of Systems Biology for Medicine, Fudan University, Shanghai, China. qqh@fudan.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101661034%22">Cell discovery</searchLink> [Cell Discov] 2026 Mar 31; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Mar 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101661034 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2056-5968 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220565968%22">20565968 </searchLink><i>NLM ISO Abbreviation: </i>Cell Discov <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41421-026-00878-5
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              Text: 2026 Mar 31
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