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Molecular Engineering of the Helminth TGF-β Mimetics, TGM1 and TGM4, Reveals a Novel Antagonist of TGF-β Signaling in Fibroblasts.

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Title: Molecular Engineering of the Helminth TGF-β Mimetics, TGM1 and TGM4, Reveals a Novel Antagonist of TGF-β Signaling in Fibroblasts.
Authors: Cunningham KT; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.; Champalimaud Centre for the Unknown, Lisbon, Portugal., Ciancia C; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.; Erasmus MC Department of Viroscience, Rotterdam, the Netherlands., Campion T; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.; INSERM, University of Toulouse, Toulouse, France., van Dinther M; Oncode Institute and Department of Cell and Chemical Biology, University of Leiden, Leiden, the Netherlands., Davis N; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK., Duffy A; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK., Heawood ALL; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK., Power L; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.; Division of Immunology, Immunity to Infection and Respiratory Medicine, University of Manchester, Manchester, UK., Sanders A; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.; Department of Neuroscience, NYU Langone Health Grossman School of Medicine, New York, New York, USA., Singh SP; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.; Department of Biological Sciences, Birla Institute of Technology and Science, Pilani, Rajasthan, India., Smyth DJ; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.; Division of Cell Signalling and Immunology, University of Dundee, Dundee, UK., Thompson E; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK., White R; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK., Hinck AP; Department of Structural Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ten Dijke P; Oncode Institute and Department of Cell and Chemical Biology, University of Leiden, Leiden, the Netherlands., Maizels RM; Centre for Parasitology, School of Infection and Immunity, University of Glasgow, Glasgow, UK.
Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2026 Apr 15; Vol. 40 (7), pp. e71338.
Publication Type: Journal Article
Journal Info: Publisher: Federation of American Societies for Experimental Biology Country of Publication: United States NLM ID: 8804484 Publication Model: Print Cited Medium: Internet ISSN: 1530-6860 (Electronic) Linking ISSN: 08926638 NLM ISO Abbreviation: FASEB J Subsets: MEDLINE
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  Data: Molecular Engineering of the Helminth TGF-β Mimetics, TGM1 and TGM4, Reveals a Novel Antagonist of TGF-β Signaling in Fibroblasts.
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