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Lenalidomide plus rituximab for previously untreated advanced follicular lymphoma: the 10-year RELEVANCE trial analysis.

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Title: Lenalidomide plus rituximab for previously untreated advanced follicular lymphoma: the 10-year RELEVANCE trial analysis.
Authors: Gower N; Service des Maladies du Sang, Centre Hospitalier Universitaire de Lille, Université de Lille, Lille, France., Feugier P; Service Hématologie, Centre Hospitalier Régional Universitaire de Nancy-Hôpital Brabois, Université de Lorraine, Nancy, France., Westin J; Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX., Schiano De Colella JM; Département Hématologie, Institut Paoli Calmettes, Marseille, France., Tilly H; Service Hématologie, Centre Henri Becquerel, Rouen, France., Palomba ML; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY., Julia E; Service d'Hématologie, Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite, France., Damaj GL; Institut d'Hématologie de Basse Normandie, Caen, France., Durand A; Service Hématologie Clinique, Centre Hospitalier Universitaire Dijon Bourgogne, Dijon, France., Flinn I; OneOncology and Tennessee Oncology, Nashville, TN., Lemonnier F; Service d'Hématologie Lymphoïde, Henri Mondor Université Hôpital-Université Paris-Est Créteil, Créteil, France., Morineau N; Service Hématologie, Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France., Ysebaert L; Service Hématologie, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France., Bartlett N; Department of Hematology and Oncology, Washington University School of Medicine Siteman Cancer Center Hematology Labs, St. Louis, MO., Thieblemont C; Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Hémato-Oncologie and Université Paris Cité, Paris, France., Ribrag V; Département d'hématologie-Département d'Innovation Thérapeutique et des Essais Précoces, Gustave Roussy, Villejuif, France., Gastinne T; Service Hématologie, Centre Hospitalier Universitaire de Nantes, Nantes, France., Dony A; Service Hématologie, Centre Hospitalier Metropole Savoie Chambéry, Chambéry, France., Fouillet L; Service Hématologie, Institut de Cancérologie et d'Hématologie Universitaire de Saint-Étienne, Saint-Priest-en-Jarez, France., Guidez S; Service d'Oncologie Hématologique et Thérapie Cellulaire, Centre Hospitalier Universitaire de Poitiers-Hôpital de la Miletrie, Poitiers, France., Houot R; Service d'Hématologie, Centre Hospitalier Universitaire Pontchaillou, Rennes, France., Da Silva MG; Departamento Hematologia, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisboa, Portugal., Barnes J; Department of Hematology and Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA., Bijou F; Service d'Hématologie, Institut Bergonie, Bordeaux, France., Cartron G; Département d'Hématologie Clinique, Centre Hospitalier Universitaire de Montpellier, Montpellier, France., Garcia-Sancho AM; Hematology Department, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Centro de Investigación Biomédica en Red de Cáncer, University of Salamanca, Salamanca, Spain., Eradat H; Department of Hematology and Oncology, Santa Monica Cancer Care, Santa Monica, CA., Cheminant M; Service Hématologie Adultes, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France., Guillermo AL; Department of Hematology, Hospital Clinic Barcelona, Barcelona, Spain., Abrisqueta P; Department of Hematology, Hospital Vall D'Hebron, Barcelona, Spain., Abraham J; Service Hématologie Clinique et Thérapie Cellulaire, Centre Hospitalier Universitaire de Limoges-Hôpital Dupuytren, Limoges, France., Sarkozy C; Service Hématologie, Institut Curie-Site Saint-Cloud, Saint-Cloud, France., Izutsu K; Department of Hematology, Toranomon Hospital, Tokyo, Japan.; Department of Hematology, National Cancer Center Hospital, Tokyo, Japan., Crochet G; Service Hématologie, Centre Hospitalier Universitaire UCL Namur-Site Godinne, Yvoir, Belgium., Sehn LH; BC Cancer Centre for Lymphoid Cancer and Department of Medical Oncology, The University of British Columbia, Vancouver, Canada., Gkasiamis A; Bristol Myers Squibb, Boudry, Switzerland., Yge ML; Bristol Myers Squibb, Boudry, Switzerland., Chartier L; Biostatistics Department, Lymphoma Study Academic Research Organisation, Centre Hospitalier Lyon Sud, Pierre Benite Cedex, France., Fowler N; Department of Hematology and Oncology, MD Anderson Cancer Center, Houston, TX., Xerri L; Aix Marseille Université, INSERM, Centre National de la Recherche Scientifique, Institut Paoli-Calmettes, Cancer Research Center of Marseille, Marseille, France., Salles G; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY., Morschhauser F; Service des Maladies du Sang, Centre Hospitalier Universitaire de Lille, Université de Lille, Lille, France.; Groupe de Recherche sur les Formes Injectables et les Technologies Associées (ULR7365), Université de Lille, Lille, France.
Source: Blood [Blood] 2026 Jun 18; Vol. 147 (25), pp. 3061-3068.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Lenalidomide plus rituximab for previously untreated advanced follicular lymphoma: the 10-year RELEVANCE trial analysis.
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  Data: <searchLink fieldCode="AU" term="%22Gower+N%22">Gower N</searchLink>; Service des Maladies du Sang, Centre Hospitalier Universitaire de Lille, Université de Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Feugier+P%22">Feugier P</searchLink>; Service Hématologie, Centre Hospitalier Régional Universitaire de Nancy-Hôpital Brabois, Université de Lorraine, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Westin+J%22">Westin J</searchLink>; Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Schiano+De+Colella+JM%22">Schiano De Colella JM</searchLink>; Département Hématologie, Institut Paoli Calmettes, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Tilly+H%22">Tilly H</searchLink>; Service Hématologie, Centre Henri Becquerel, Rouen, France.<br /><searchLink fieldCode="AU" term="%22Palomba+ML%22">Palomba ML</searchLink>; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Julia+E%22">Julia E</searchLink>; Service d'Hématologie, Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite, France.<br /><searchLink fieldCode="AU" term="%22Damaj+GL%22">Damaj GL</searchLink>; Institut d'Hématologie de Basse Normandie, Caen, France.<br /><searchLink fieldCode="AU" term="%22Durand+A%22">Durand A</searchLink>; Service Hématologie Clinique, Centre Hospitalier Universitaire Dijon Bourgogne, Dijon, France.<br /><searchLink fieldCode="AU" term="%22Flinn+I%22">Flinn I</searchLink>; OneOncology and Tennessee Oncology, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Lemonnier+F%22">Lemonnier F</searchLink>; Service d'Hématologie Lymphoïde, Henri Mondor Université Hôpital-Université Paris-Est Créteil, Créteil, France.<br /><searchLink fieldCode="AU" term="%22Morineau+N%22">Morineau N</searchLink>; Service Hématologie, Centre Hospitalier Départemental Vendée, La Roche-sur-Yon, France.<br /><searchLink fieldCode="AU" term="%22Ysebaert+L%22">Ysebaert L</searchLink>; Service Hématologie, Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Bartlett+N%22">Bartlett N</searchLink>; Department of Hematology and Oncology, Washington University School of Medicine Siteman Cancer Center Hematology Labs, St. Louis, MO.<br /><searchLink fieldCode="AU" term="%22Thieblemont+C%22">Thieblemont C</searchLink>; Assistance Publique-Hôpitaux de Paris, Hôpital Saint-Louis, Hémato-Oncologie and Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Ribrag+V%22">Ribrag V</searchLink>; Département d'hématologie-Département d'Innovation Thérapeutique et des Essais Précoces, Gustave Roussy, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Gastinne+T%22">Gastinne T</searchLink>; Service Hématologie, Centre Hospitalier Universitaire de Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Dony+A%22">Dony A</searchLink>; Service Hématologie, Centre Hospitalier Metropole Savoie Chambéry, Chambéry, France.<br /><searchLink fieldCode="AU" term="%22Fouillet+L%22">Fouillet L</searchLink>; Service Hématologie, Institut de Cancérologie et d'Hématologie Universitaire de Saint-Étienne, Saint-Priest-en-Jarez, France.<br /><searchLink fieldCode="AU" term="%22Guidez+S%22">Guidez S</searchLink>; Service d'Oncologie Hématologique et Thérapie Cellulaire, Centre Hospitalier Universitaire de Poitiers-Hôpital de la Miletrie, Poitiers, France.<br /><searchLink fieldCode="AU" term="%22Houot+R%22">Houot R</searchLink>; Service d'Hématologie, Centre Hospitalier Universitaire Pontchaillou, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Da+Silva+MG%22">Da Silva MG</searchLink>; Departamento Hematologia, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisboa, Portugal.<br /><searchLink fieldCode="AU" term="%22Barnes+J%22">Barnes J</searchLink>; Department of Hematology and Oncology, Harvard Medical School, Massachusetts General Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Bijou+F%22">Bijou F</searchLink>; Service d'Hématologie, Institut Bergonie, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Cartron+G%22">Cartron G</searchLink>; Département d'Hématologie Clinique, Centre Hospitalier Universitaire de Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Garcia-Sancho+AM%22">Garcia-Sancho AM</searchLink>; Hematology Department, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca, Centro de Investigación Biomédica en Red de Cáncer, University of Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Eradat+H%22">Eradat H</searchLink>; Department of Hematology and Oncology, Santa Monica Cancer Care, Santa Monica, CA.<br /><searchLink fieldCode="AU" term="%22Cheminant+M%22">Cheminant M</searchLink>; Service Hématologie Adultes, Hôpital Universitaire Necker-Enfants Malades, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.<br /><searchLink fieldCode="AU" term="%22Guillermo+AL%22">Guillermo AL</searchLink>; Department of Hematology, Hospital Clinic Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Abrisqueta+P%22">Abrisqueta P</searchLink>; Department of Hematology, Hospital Vall D'Hebron, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Abraham+J%22">Abraham J</searchLink>; Service Hématologie Clinique et Thérapie Cellulaire, Centre Hospitalier Universitaire de Limoges-Hôpital Dupuytren, Limoges, France.<br /><searchLink fieldCode="AU" term="%22Sarkozy+C%22">Sarkozy C</searchLink>; Service Hématologie, Institut Curie-Site Saint-Cloud, Saint-Cloud, France.<br /><searchLink fieldCode="AU" term="%22Izutsu+K%22">Izutsu K</searchLink>; Department of Hematology, Toranomon Hospital, Tokyo, Japan.; Department of Hematology, National Cancer Center Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Crochet+G%22">Crochet G</searchLink>; Service Hématologie, Centre Hospitalier Universitaire UCL Namur-Site Godinne, Yvoir, Belgium.<br /><searchLink fieldCode="AU" term="%22Sehn+LH%22">Sehn LH</searchLink>; BC Cancer Centre for Lymphoid Cancer and Department of Medical Oncology, The University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Gkasiamis+A%22">Gkasiamis A</searchLink>; Bristol Myers Squibb, Boudry, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yge+ML%22">Yge ML</searchLink>; Bristol Myers Squibb, Boudry, Switzerland.<br /><searchLink fieldCode="AU" term="%22Chartier+L%22">Chartier L</searchLink>; Biostatistics Department, Lymphoma Study Academic Research Organisation, Centre Hospitalier Lyon Sud, Pierre Benite Cedex, France.<br /><searchLink fieldCode="AU" term="%22Fowler+N%22">Fowler N</searchLink>; Department of Hematology and Oncology, MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Xerri+L%22">Xerri L</searchLink>; Aix Marseille Université, INSERM, Centre National de la Recherche Scientifique, Institut Paoli-Calmettes, Cancer Research Center of Marseille, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Salles+G%22">Salles G</searchLink>; Lymphoma Service, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Morschhauser+F%22">Morschhauser F</searchLink>; Service des Maladies du Sang, Centre Hospitalier Universitaire de Lille, Université de Lille, Lille, France.; Groupe de Recherche sur les Formes Injectables et les Technologies Associées (ULR7365), Université de Lille, Lille, France.
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