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Brown adipose-derived mesenchymal stromal cells improve sepsis-induced multiorgan dysfunction more than white adipose cells in obese rats.

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Title: Brown adipose-derived mesenchymal stromal cells improve sepsis-induced multiorgan dysfunction more than white adipose cells in obese rats.
Authors: Silva JD; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Lopes-Pacheco M; Department of Pediatrics, Center for Cystic Fibrosis and Airway Disease Research, Emory University School of Medicine, Atlanta, GA, USA., de Carvalho LRP; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Abreu SC; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., da Silva MMA; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Melo MM; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Cabral MR; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., de Souza CMR; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Santos RT; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Vieira JB; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Castro LL; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Rodrigues GC; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Weiss DJ; Department of Medicine, University of Vermont, Burlington, VT, USA., Silva PL; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil., Cruz FF; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil., Morales MM; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Rocco PRM; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil. Electronic address: prmrocco@biof.ufrj.br.
Source: Cytotherapy [Cytotherapy] 2026 Jun; Vol. 28 (6), pp. 102134. Date of Electronic Publication: 2026 Feb 23.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 100895309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2566 (Electronic) Linking ISSN: 14653249 NLM ISO Abbreviation: Cytotherapy Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Brown adipose-derived mesenchymal stromal cells improve sepsis-induced multiorgan dysfunction more than white adipose cells in obese rats.
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  Data: <searchLink fieldCode="AU" term="%22Silva+JD%22">Silva JD</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Lopes-Pacheco+M%22">Lopes-Pacheco M</searchLink>; Department of Pediatrics, Center for Cystic Fibrosis and Airway Disease Research, Emory University School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22de+Carvalho+LRP%22">de Carvalho LRP</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Abreu+SC%22">Abreu SC</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+MMA%22">da Silva MMA</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Melo+MM%22">Melo MM</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Cabral+MR%22">Cabral MR</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Souza+CMR%22">de Souza CMR</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Santos+RT%22">Santos RT</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Vieira+JB%22">Vieira JB</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Castro+LL%22">Castro LL</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+GC%22">Rodrigues GC</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Weiss+DJ%22">Weiss DJ</searchLink>; Department of Medicine, University of Vermont, Burlington, VT, USA.<br /><searchLink fieldCode="AU" term="%22Silva+PL%22">Silva PL</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Cruz+FF%22">Cruz FF</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Morales+MM%22">Morales MM</searchLink>; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil; Laboratory of Cellular and Molecular Physiology, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Rocco+PRM%22">Rocco PRM</searchLink>; Laboratory of Pulmonary Investigation, Carlos Chagas Biophysics Institute, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil; National Institute of Science and Technology for Regenerative Medicine, Rio de Janeiro, RJ, Brazil. Electronic address: prmrocco@biof.ufrj.br.
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  Data: <searchLink fieldCode="JN" term="%22100895309%22">Cytotherapy</searchLink> [Cytotherapy] 2026 Jun; Vol. 28 (6), pp. 102134. <i>Date of Electronic Publication: </i>2026 Feb 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100895309 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-2566 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214653249%22">14653249 </searchLink><i>NLM ISO Abbreviation: </i>Cytotherapy <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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