Beta cell-targeted PD-1 agonist inhibits cell-mediated autoimmunity in pancreas tissue slices.
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| Title: | Beta cell-targeted PD-1 agonist inhibits cell-mediated autoimmunity in pancreas tissue slices. |
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| Authors: | Becker MW; J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA., Brown ME; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA., Wiseman K; Immunocore Ltd., Abingdon, UK., Chiodetti AL; Immunocore Ltd., Abingdon, UK., Huber MK; J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA.; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA., Cuaycal AE; J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA.; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Infectious Diseases and Immunology, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA., Sintara P; J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA., Ferreira SM; J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA., Smurlick D; J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA., Barra JM; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pharmacology & Therapeutics, College of Medicine, University of Florida, Gainesville, FL, USA., Ladd AM; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pharmacology & Therapeutics, College of Medicine, University of Florida, Gainesville, FL, USA., Drotar DM; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA., Atkinson MA; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, USA., Weber P; Immunocore Ltd., Abingdon, UK., Al-Mossawi H; Immunocore Ltd., Abingdon, UK., Russ HA; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pharmacology & Therapeutics, College of Medicine, University of Florida, Gainesville, FL, USA., Mahon TM; Immunocore Ltd., Abingdon, UK., Brusko TM; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA.; Department of Pediatrics, College of Medicine, University of Florida, Gainesville, FL, USA.; Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA., Bossi G; Immunocore Ltd., Abingdon, UK., Phelps EA; J. Crayton Pruitt Family Department of Biomedical Engineering, Herbert Wertheim College of Engineering, University of Florida, Gainesville, FL, USA.; Department of Pathology, Immunology, and Laboratory Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.; University of Florida Diabetes Institute, University of Florida, Gainesville, FL, USA. |
| Source: | Science advances [Sci Adv] 2026 Apr 03; Vol. 12 (14), pp. eaec9029. Date of Electronic Publication: 2026 Apr 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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