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LATS1/2 Inhibitor Attenuates Osteoclast Differentiation via Hippo-YAP/TAZ Signaling Pathway and Alleviates Osteoporosis in Ovariectomized Rats.

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Title: LATS1/2 Inhibitor Attenuates Osteoclast Differentiation via Hippo-YAP/TAZ Signaling Pathway and Alleviates Osteoporosis in Ovariectomized Rats.
Authors: Chen SH; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China., Jiang Y; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China., Xie GQ; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China., Fang ZH; Department of Orthopaedics, Zhejiang Chinese Medical University Master Degree Cultivation Base in Jiaxing University, Jiaxing, 314000, China., Zhang BY; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China., Jiang CY; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China. jiangfandd2@163.com., Zhu JY; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China. zhujinyu@zjxu.edu.cn.
Source: Current medical science [Curr Med Sci] 2026 Apr; Vol. 46 (2), pp. 506-517. Date of Electronic Publication: 2026 Apr 01.
Publication Type: Journal Article
Journal Info: Publisher: Huazhong University of Science and Technology Country of Publication: China NLM ID: 101729993 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2523-899X (Electronic) Linking ISSN: 2523899X NLM ISO Abbreviation: Curr Med Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: LATS1/2 Inhibitor Attenuates Osteoclast Differentiation via Hippo-YAP/TAZ Signaling Pathway and Alleviates Osteoporosis in Ovariectomized Rats.
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  Data: <searchLink fieldCode="AU" term="%22Chen+SH%22">Chen SH</searchLink>; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China.<br /><searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China.<br /><searchLink fieldCode="AU" term="%22Xie+GQ%22">Xie GQ</searchLink>; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China.<br /><searchLink fieldCode="AU" term="%22Fang+ZH%22">Fang ZH</searchLink>; Department of Orthopaedics, Zhejiang Chinese Medical University Master Degree Cultivation Base in Jiaxing University, Jiaxing, 314000, China.<br /><searchLink fieldCode="AU" term="%22Zhang+BY%22">Zhang BY</searchLink>; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China.<br /><searchLink fieldCode="AU" term="%22Jiang+CY%22">Jiang CY</searchLink>; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China. jiangfandd2@163.com.<br /><searchLink fieldCode="AU" term="%22Zhu+JY%22">Zhu JY</searchLink>; Department of Orthopaedics, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, 314000, China. zhujinyu@zjxu.edu.cn.
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      – TitleFull: LATS1/2 Inhibitor Attenuates Osteoclast Differentiation via Hippo-YAP/TAZ Signaling Pathway and Alleviates Osteoporosis in Ovariectomized Rats.
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              Text: 2026 Apr
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