From barrier to bridge: a scoping review on the methods, clinical efficacy, and safety of blood-brain barrier disruption in treating high-grade glioma.
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| Title: | From barrier to bridge: a scoping review on the methods, clinical efficacy, and safety of blood-brain barrier disruption in treating high-grade glioma. |
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| Authors: | Dufault ME; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Akhavan-Sigari A; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Pachón-Londoño MJ; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Olson VA; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Turcotte EL; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Mayo Clinic Alix School of Medicine, Phoenix, AZ, USA., Beniwal AS; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Mayo Clinic Alix School of Medicine, Phoenix, AZ, USA.; Department of Cancer Biology, Mayo Clinic, Phoenix, AZ, USA., Carlson BH; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Mayo Clinic Alix School of Medicine, Phoenix, AZ, USA., Moussalem CK; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Giotta Lucifero A; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Bathini AR; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Bossi Todeschini A; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA., Porter AB; Department of Neurology, Mayo Clinic, Phoenix, AZ, USA., Mrugala MM; Department of Neurology, Mayo Clinic, Phoenix, AZ, USA., Fortin Ensign S; Department of Cancer Biology, Mayo Clinic, Phoenix, AZ, USA.; Division of Hematology and Oncology, Department of Internal Medicine, Mayo Clinic, Phoenix, AZ, USA., Turkmani AH; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Mayo Clinic Alix School of Medicine, Phoenix, AZ, USA., Krishna C; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.; Mayo Clinic Alix School of Medicine, Phoenix, AZ, USA., Bendok BR; Department of Neurological Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA. Bendok.bernard@mayo.edu.; Neurosurgery Simulation and Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA. Bendok.bernard@mayo.edu.; Precision Neuro-Therapeutics Innovation Laboratory, Mayo Clinic, Phoenix, AZ, USA. Bendok.bernard@mayo.edu.; Mayo Clinic Alix School of Medicine, Phoenix, AZ, USA. Bendok.bernard@mayo.edu.; Department of Radiology, Mayo Clinic, Phoenix, AZ, USA. Bendok.bernard@mayo.edu.; Department of Otolaryngology - Head & Neck Surgery, Mayo Clinic, Phoenix, AZ, USA. Bendok.bernard@mayo.edu.; Chair, Department of Neurological Surgery, Mayo Clinic, Phoenix, AZ, USA. Bendok.bernard@mayo.edu. |
| Source: | Journal of neuro-oncology [J Neurooncol] 2026 Apr 01; Vol. 177 (2). Date of Electronic Publication: 2026 Apr 01. |
| Publication Type: | Journal Article; Scoping Review; Review |
| Journal Info: | Publisher: Springer Country of Publication: United States NLM ID: 8309335 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7373 (Electronic) Linking ISSN: 0167594X NLM ISO Abbreviation: J Neurooncol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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