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The evolving landscape of large language models and non-large language models in health care.

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Title: The evolving landscape of large language models and non-large language models in health care.
Authors: Yang R; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; These authors contributed equally: Rui Yang, Huitao Li., Li H; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; These authors contributed equally: Rui Yang, Huitao Li., Heng Wong MY; School of Clinical Medicine, University of Cambridge, Cambridge, UK., Ke Y; Division of Anesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore, Singapore., Li X; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore., Yu K; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore., Liao J; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore., Kai Liew JC; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore., Nair SV; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore., Ong JCL; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; Division of Pharmacy, Singapore General Hospital, Singapore, Singapore., Li I; Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Teodoro D; Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Hong C; Department of Biostatistics and Bioinformatics, Duke School of Medicine, Durham, NC, USA.; Duke Clinical Research Institute, Durham, NC, USA., Peng Y; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA., Ting DSW; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Byers Eye Institute, Stanford University, Stanford, CA, USA.; Artificial Intelligence Office, Singapore Health Services, Singapore, Singapore., Liu N; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; Department of Biostatistics and Bioinformatics, Duke School of Medicine, Durham, NC, USA.; Programme in Health Services Research & Population Health, Duke-NUS Medical School, Singapore, Singapore.; NUS Artificial Intelligence Institute, National University of Singapore, Singapore, Singapore.
Source: Npj health systems [Npj Health Syst] 2026; Vol. 3. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 9918956761506676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 3005-1959 (Electronic) Linking ISSN: 30051959 NLM ISO Abbreviation: Npj Health Syst Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Yang+R%22">Yang R</searchLink>; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; These authors contributed equally: Rui Yang, Huitao Li.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; These authors contributed equally: Rui Yang, Huitao Li.<br /><searchLink fieldCode="AU" term="%22Heng+Wong+MY%22">Heng Wong MY</searchLink>; School of Clinical Medicine, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Ke+Y%22">Ke Y</searchLink>; Division of Anesthesiology and Perioperative Medicine, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Yu+K%22">Yu K</searchLink>; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Liao+J%22">Liao J</searchLink>; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Kai+Liew+JC%22">Kai Liew JC</searchLink>; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; School of Chemistry, Chemical Engineering and Biotechnology, Nanyang Technological University, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Nair+SV%22">Nair SV</searchLink>; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Ong+JCL%22">Ong JCL</searchLink>; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; Division of Pharmacy, Singapore General Hospital, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Li+I%22">Li I</searchLink>; Graduate School of Engineering, The University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Teodoro+D%22">Teodoro D</searchLink>; Department of Radiology and Medical Informatics, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hong+C%22">Hong C</searchLink>; Department of Biostatistics and Bioinformatics, Duke School of Medicine, Durham, NC, USA.; Duke Clinical Research Institute, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Peng+Y%22">Peng Y</searchLink>; Department of Population Health Sciences, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ting+DSW%22">Ting DSW</searchLink>; Singapore Eye Research Institute, Singapore National Eye Center, Singapore, Singapore.; Byers Eye Institute, Stanford University, Stanford, CA, USA.; Artificial Intelligence Office, Singapore Health Services, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; Center for Biomedical Data Science, Duke-NUS Medical School, Singapore, Singapore.; Duke-NUS AI + Medical Sciences Initiative, Duke-NUS Medical School, Singapore, Singapore.; Department of Biostatistics and Bioinformatics, Duke School of Medicine, Durham, NC, USA.; Programme in Health Services Research & Population Health, Duke-NUS Medical School, Singapore, Singapore.; NUS Artificial Intelligence Institute, National University of Singapore, Singapore, Singapore.
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  Data: <searchLink fieldCode="JN" term="%229918956761506676%22">Npj health systems</searchLink> [Npj Health Syst] 2026; Vol. 3. <i>Date of Electronic Publication: </i>2026 Mar 09.
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        Value: 10.1038/s44401-026-00076-1
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        Text: English
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