Peripheral blood UBA1 variant burden predicts poor outcomes in VEXAS syndrome: a nationwide prospective study.
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| Title: | Peripheral blood UBA1 variant burden predicts poor outcomes in VEXAS syndrome: a nationwide prospective study. |
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| Authors: | Kirino Y; Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan. Electronic address: kirino@yokohama-cu.ac.jp., Maeda A; Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Higashitani K; Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Horita N; Chemotherapy Center, Yokohama City University Hospital, Yokohama, Japan., Asano T; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan., Migita K; Department of Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan., Motomura Y; Division of Rheumatology, Department of Internal Medicine, Kameda Medical Center, Kamogawa, Japan., Rokutanda R; Division of Rheumatology, Department of Internal Medicine, Kameda Medical Center, Kamogawa, Japan., Kobayashi D; Division of Clinical Nephrology and Rheumatology, Kidney Research Center, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan., Tamura M; Department of Diabetes, Endocrinology and Clinical Immunology, Hyogo Medical University, Nishinomiya, Japan., Kanazawa N; Department of Dermatology, Hyogo Medical University, Nishinomiya, Japan., Furuhashi K; Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Kondo Y; Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Nagahata K; Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan., Takahashi H; Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan., Kobayashi H; Department of Rheumatology, Tokyo Medical University Hachioji Medical Center, Hachioji, Japan., Yao S; Department of Internal Medicine, Osaka City General Hospital, Osaka, Japan., Yamagami K; Department of Internal Medicine, Osaka City General Hospital, Osaka, Japan., Uchino K; Division of Hematology, Department of Internal Medicine, Aichi Medical University, Nagakute, Japan., Hidaka Y; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Ida H; Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Kishida D; Department of Medicine (Neurology & Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan., Sato T; Department of Rheumatology, Shimane University Faculty of Medicine, Izumo, Japan., Ichinose K; Department of Rheumatology, Shimane University Faculty of Medicine, Izumo, Japan., Miyamae T; Department of Pediatric Rheumatology, Tokyo Women's Medical University Hospital, Tokyo, Japan., Tsujimoto K; Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine, Suita, Japan., Inoue Y; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine, Hokkaido University, Sapporo, Japan., Fujieda Y; Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine, Hokkaido University, Sapporo, Japan., Mishima K; Center for Rheumatic Diseases, Matsuyama Red Cross Hospital, Matsuyama, Japan., Tsuji T; Center for Rheumatic Diseases, Matsuyama Red Cross Hospital, Matsuyama, Japan., Tanaka K; Department of Respiratory Medicine, Fujieda Municipal General Hospital, Fujieda, Japan., Noda H; Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Isogai S; Department of Respiratory Medicine, Allergy and Clinical Immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Miyoshi Y; Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Fuchū, Japan., Yokogawa N; Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Fuchū, Japan., Ota S; Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Sakuraba H; Department of Gastroenterology, Hematology and Clinical Immunology, Hirosaki University Graduate School of Medicine, Hirosaki, Japan., Nishi J; Division of Dermatology, Faculty of Medicine, Saga University, Saga, Japan., Inoue T; Division of Dermatology, Faculty of Medicine, Saga University, Saga, Japan., Muraoka S; Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan., Nanki T; Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Tokyo, Japan., Shimizu T; Departments of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Koga T; Departments of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan., Inaba Y; Department of Dermatology, Wakayama Medical University, Wakayama, Japan., Matsubara M; Department of General Medicine, Nara Medical University, Kashihara, Japan., Yoshimoto K; Department of General Medicine, Nara Medical University, Kashihara, Japan., Hasegawa A; Department of Rheumatology, Dokkyo Medical University, Mibu, Japan., Ikeda K; Department of Rheumatology, Dokkyo Medical University, Mibu, Japan., Motohashi R; Department of Rheumatology and Nephrology, Japanese Red Cross Maebashi Hospital, Maebashi, Japan., Takeuchi Y; Department of Rheumatology and Nephrology, Japanese Red Cross Maebashi Hospital, Maebashi, Japan., Shiratsuchi M; Department of Hematology, Iizuka Hospital, Iizuka, Japan., Moriyama M; Division of Rheumatology, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan., Noda K; Division of Rheumatology, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan., Saito S; Department of Rheumatology, Yokohama City Minato Red Cross Hospital, Yokohama, Japan., Hagiyama H; Department of Rheumatology, Yokohama City Minato Red Cross Hospital, Yokohama, Japan., Honda T; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan., Kageyama R; Department of Dermatology, Hamamatsu University School of Medicine, Hamamatsu, Japan., Nakatani N; Department of Hematology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan., Goto T; Department of Hematology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan., Kishimoto M; Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Mitaka, Japan., Watanabe T; Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Yamaguchi Y; Department of Environmental Immuno-Dermatology, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Nishikomori R; Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Japan., Ohara O; Department of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Japan., Ban T; Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Tamura T; Department of Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Nakajima H; Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan. |
| Source: | Annals of the rheumatic diseases [Ann Rheum Dis] 2026 Apr 01. Date of Electronic Publication: 2026 Apr 01. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: United States NLM ID: 0372355 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-2060 (Electronic) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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