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An Enhanced Treatment Algorithm Targeting Mucosal Healing Is Effective and Safe in Older Patients With Crohn's Disease: A Post Hoc Analysis of the REACT2 Trial.

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Title: An Enhanced Treatment Algorithm Targeting Mucosal Healing Is Effective and Safe in Older Patients With Crohn's Disease: A Post Hoc Analysis of the REACT2 Trial.
Authors: Goodwin SW; Lawson Health Research Institute, London Health Science Centre, London, Ontario, Canada., Vuyyuru SK; Departments of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada., Sedano R; Lawson Health Research Institute, London Health Science Centre, London, Ontario, Canada.; Departments of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada.; Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada., Zou G; Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada., Dulai PS; Division of Gastroenterology, Department of Medicine, Northwestern University, Chicago, Illinois, USA., Singh S; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA., Narula N; Department of Medicine, Division of Gastroenterology, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada., Ma C; Division of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada ., Jairath V; Lawson Health Research Institute, London Health Science Centre, London, Ontario, Canada.; Departments of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada.; Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada.
Source: The American journal of gastroenterology [Am J Gastroenterol] 2026 Apr 03. Date of Electronic Publication: 2026 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health Country of Publication: United States NLM ID: 0421030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1572-0241 (Electronic) Linking ISSN: 00029270 NLM ISO Abbreviation: Am J Gastroenterol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: An Enhanced Treatment Algorithm Targeting Mucosal Healing Is Effective and Safe in Older Patients With Crohn's Disease: A Post Hoc Analysis of the REACT2 Trial.
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  Data: <searchLink fieldCode="AU" term="%22Goodwin+SW%22">Goodwin SW</searchLink>; Lawson Health Research Institute, London Health Science Centre, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Vuyyuru+SK%22">Vuyyuru SK</searchLink>; Departments of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Sedano+R%22">Sedano R</searchLink>; Lawson Health Research Institute, London Health Science Centre, London, Ontario, Canada.; Departments of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada.; Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zou+G%22">Zou G</searchLink>; Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Dulai+PS%22">Dulai PS</searchLink>; Division of Gastroenterology, Department of Medicine, Northwestern University, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Singh+S%22">Singh S</searchLink>; Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic Arizona, Scottsdale, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Narula+N%22">Narula N</searchLink>; Department of Medicine, Division of Gastroenterology, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Ma+C%22">Ma C</searchLink>; Division of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada .<br /><searchLink fieldCode="AU" term="%22Jairath+V%22">Jairath V</searchLink>; Lawson Health Research Institute, London Health Science Centre, London, Ontario, Canada.; Departments of Medicine, Division of Gastroenterology, Western University, London, Ontario, Canada.; Department of Epidemiology & Biostatistics, Western University, London, Ontario, Canada.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%22">Wolters Kluwer Health </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0421030 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1572-0241 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200029270%22">00029270 </searchLink><i>NLM ISO Abbreviation: </i>Am J Gastroenterol <i>Subsets: </i>MEDLINE
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        Text: English
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              Text: 2026 Apr 03
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