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Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF.

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Title: Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF.
Authors: Ma B; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Lyu W; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Rizk J; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Han X; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kjær M; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Pereira Almeida V; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Jessen M; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Sauerland MB; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark., Leung CSK; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Centre for Immuno-Oncology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Van den Eynde BJ; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Ludwig Institute for Cancer Research, de Duve Institute, UCLouvain, Brussels, Belgium.; WELBIO Department, WEL Research Institute, Brussels, Belgium., Lu X; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Gyrd-Hansen M; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Source: Science immunology [Sci Immunol] 2026 Apr 03; Vol. 11 (118), pp. eaeb6484. Date of Electronic Publication: 2026 Apr 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF.
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  Data: <searchLink fieldCode="AU" term="%22Ma+B%22">Ma B</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lyu+W%22">Lyu W</searchLink>; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rizk+J%22">Rizk J</searchLink>; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Han+X%22">Han X</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Kjær+M%22">Kjær M</searchLink>; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Pereira+Almeida+V%22">Pereira Almeida V</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Jessen+M%22">Jessen M</searchLink>; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Sauerland+MB%22">Sauerland MB</searchLink>; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Leung+CSK%22">Leung CSK</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Centre for Immuno-Oncology, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Van+den+Eynde+BJ%22">Van den Eynde BJ</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Ludwig Institute for Cancer Research, de Duve Institute, UCLouvain, Brussels, Belgium.; WELBIO Department, WEL Research Institute, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Lu+X%22">Lu X</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Gyrd-Hansen+M%22">Gyrd-Hansen M</searchLink>; Ludwig Institute for Cancer Research, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; LEO Foundation Skin Immunology Research Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
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  Data: <searchLink fieldCode="JN" term="%22101688624%22">Science immunology</searchLink> [Sci Immunol] 2026 Apr 03; Vol. 11 (118), pp. eaeb6484. <i>Date of Electronic Publication: </i>2026 Apr 03.
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