Irisin ameliorates obesity and insulin resistance via adipose tissue IL-33 and regulatory T cells.
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| Title: | Irisin ameliorates obesity and insulin resistance via adipose tissue IL-33 and regulatory T cells. |
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| Authors: | A M; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Wang G; Department of Immunology, Harvard Medical School, Boston, MA, USA.; Institute of Modern Biology, Nanjing University, Nanjing, China., Zammit NW; Department of Immunology, Harvard Medical School, Boston, MA, USA., Roth L; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Maierhaba Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Bogoslavski D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Cai C; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Langston PK; Department of Immunology, Harvard Medical School, Boston, MA, USA.; Department of Pathology, Yale School of Medicine, New Haven, CT, USA.; Yale Center for Research on Aging, Yale School of Medicine, New Haven, CT, USA., Zhang Q; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA., Afonina IS; VIB Center for Inflammation Research, Gent, Belgium.; UGent Department of Biomedical Molecular Biology, Gent, Belgium., Beyaert R; VIB Center for Inflammation Research, Gent, Belgium.; UGent Department of Biomedical Molecular Biology, Gent, Belgium., Spiegelman BM; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA. bruce_spiegelman@dfci.harvard.edu.; Department of Cell Biology, Harvard Medical School, Boston, MA, USA. bruce_spiegelman@dfci.harvard.edu., Mathis D; Department of Immunology, Harvard Medical School, Boston, MA, USA. dm@hms.harvard.edu. |
| Source: | Nature metabolism [Nat Metab] 2026 Apr; Vol. 8 (4), pp. 885-901. Date of Electronic Publication: 2026 Apr 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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