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Nanobody-based targeted cancer therapy and immunotherapy: fear not the future.

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Title: Nanobody-based targeted cancer therapy and immunotherapy: fear not the future.
Authors: Guo MD; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology, College of Pharmacy, and Department of Cardiology, the Second Affiliated Hospital, Harbin Medical University, Harbin, 150081, China.; State Key Laboratory*-Province Key Laboratories of Biomedicine-Pharmaceutics of China, and Key Laboratory of Cardiovascular Research, Ministry of Education, College of Pharmacy, Harbin, 150081, China.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China., Liao R; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology, College of Pharmacy, and Department of Cardiology, the Second Affiliated Hospital, Harbin Medical University, Harbin, 150081, China.; Department of Pathology, Harbin Medical University, Harbin, 150081, China., Wang MY; College of Life Science, Northeast Agricultural University, Harbin, 150030, China., Wu LJ; College of Life Science, Northeast Agricultural University, Harbin, 150030, China., Zhang Y; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology, College of Pharmacy, and Department of Cardiology, the Second Affiliated Hospital, Harbin Medical University, Harbin, 150081, China. hmuzhangyong@hotmail.com.; State Key Laboratory*-Province Key Laboratories of Biomedicine-Pharmaceutics of China, and Key Laboratory of Cardiovascular Research, Ministry of Education, College of Pharmacy, Harbin, 150081, China. hmuzhangyong@hotmail.com.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China. hmuzhangyong@hotmail.com.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2026 Apr 06. Date of Electronic Publication: 2026 Apr 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Guo+MD%22">Guo MD</searchLink>; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology, College of Pharmacy, and Department of Cardiology, the Second Affiliated Hospital, Harbin Medical University, Harbin, 150081, China.; State Key Laboratory*-Province Key Laboratories of Biomedicine-Pharmaceutics of China, and Key Laboratory of Cardiovascular Research, Ministry of Education, College of Pharmacy, Harbin, 150081, China.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China.<br /><searchLink fieldCode="AU" term="%22Liao+R%22">Liao R</searchLink>; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology, College of Pharmacy, and Department of Cardiology, the Second Affiliated Hospital, Harbin Medical University, Harbin, 150081, China.; Department of Pathology, Harbin Medical University, Harbin, 150081, China.<br /><searchLink fieldCode="AU" term="%22Wang+MY%22">Wang MY</searchLink>; College of Life Science, Northeast Agricultural University, Harbin, 150030, China.<br /><searchLink fieldCode="AU" term="%22Wu+LJ%22">Wu LJ</searchLink>; College of Life Science, Northeast Agricultural University, Harbin, 150030, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Department of Pharmacology, College of Pharmacy, and Department of Cardiology, the Second Affiliated Hospital, Harbin Medical University, Harbin, 150081, China. hmuzhangyong@hotmail.com.; State Key Laboratory*-Province Key Laboratories of Biomedicine-Pharmaceutics of China, and Key Laboratory of Cardiovascular Research, Ministry of Education, College of Pharmacy, Harbin, 150081, China. hmuzhangyong@hotmail.com.; Research Unit of Noninfectious Chronic Diseases in Frigid Zone (2019RU070), Chinese Academy of Medical Sciences, Harbin, 150081, China. hmuzhangyong@hotmail.com.
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        Value: 10.1038/s41401-026-01787-9
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              Text: 2026 Apr 06
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