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Paternal use of metformin and risk of major congenital malformations: A meta-analysis of 4 studies.

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Title: Paternal use of metformin and risk of major congenital malformations: A meta-analysis of 4 studies.
Authors: Damkier P; Department of Clinical Pharmacology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., van Gelder MMHJ; Pharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway., Huybrechts KF; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.; Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Meng LC; Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Hernandez-Diaz S; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA., Nielsen J; Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.; Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark., Nørgård BM; Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.; Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark., Nordeng H; Pharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway.
Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2026 Jun; Vol. 92 (6), pp. 1940-1943. Date of Electronic Publication: 2026 Apr 05.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Damkier+P%22">Damkier P</searchLink>; Department of Clinical Pharmacology, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22van+Gelder+MMHJ%22">van Gelder MMHJ</searchLink>; Pharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Huybrechts+KF%22">Huybrechts KF</searchLink>; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.; Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Meng+LC%22">Meng LC</searchLink>; Graduate Institute of Clinical Pharmacy, College of Medicine, National Taiwan University, Taipei, Taiwan.; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez-Diaz+S%22">Hernandez-Diaz S</searchLink>; Department of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Nielsen+J%22">Nielsen J</searchLink>; Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.; Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark.<br /><searchLink fieldCode="AU" term="%22Nørgård+BM%22">Nørgård BM</searchLink>; Center for Clinical Epidemiology, Odense University Hospital, Odense, Denmark.; Research Unit of Clinical Epidemiology, Department of Clinical Research, University of Southern Denmark, Odense C, Denmark.<br /><searchLink fieldCode="AU" term="%22Nordeng+H%22">Nordeng H</searchLink>; Pharmacoepidemiology and Drug Safety Research Group, Department of Pharmacy, University of Oslo, Oslo, Norway.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7503323 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1365-2125 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203065251%22">03065251 </searchLink><i>NLM ISO Abbreviation: </i>Br J Clin Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1002/bcp.70547
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              Text: 2026 Jun
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