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Transcriptomic deconvolution reveals prognostic immune signatures and immunotherapy-responsive subtypes in male breast cancer.

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Title: Transcriptomic deconvolution reveals prognostic immune signatures and immunotherapy-responsive subtypes in male breast cancer.
Authors: Silvestri V; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Valentini V; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Bucalo A; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Porzio V; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Scafetta G; Translational Oncology Research Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy., Cerbelli B; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy., Zanna I; Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for cancer research, prevention and clinical network (ISPRO), Florence, Italy., Bianchi S; Department of Health Sciences, Division of Pathological Anatomy, University of Florence, Florence, Italy., Tibiletti MG; Hereditary Cancer Research Center, University of Insubria, Varese, Italy., Carnevali I; SSD Laboratorio Specialistico Genetica Medica Citogenetica e Genetica Molecolare, ASST Settelaghi Varese, Varese, Italy., Calistri D; Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori' IRCCS, Meldola, Italy., Arcangeli V; Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori' IRCCS, Meldola, Italy., Zampiga V; Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori' IRCCS, Meldola, Italy., Gasparini E; Medical Oncology, AUSL- IRCCS Reggio Emilia, Reggio Emilia, Italy., Cortesi L; Medical Oncology, AUSL- IRCCS Reggio Emilia, Reggio Emilia, Italy.; Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy., Giannini G; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy., Capalbo C; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.; Oncology Unit, Annunziata Hospital Cosenza, Cosenza, Italy., Fox SB; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology and Collaborative Centre of Cancer Genomic Medicine, University of Melbourne, Melbourne, VIC, Australia., Masala G; Clinical Epidemiology Unit, Institute for cancer research, prevention and clinical network (ISPRO), Florence, Italy., Mezi S; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy., d'Amati G; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy., Ottini L; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy. laura.ottini@uniroma1.it.
Source: Breast cancer research : BCR [Breast Cancer Res] 2026 Apr 07; Vol. 28 (1). Date of Electronic Publication: 2026 Apr 07.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100927353 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-542X (Electronic) Linking ISSN: 14655411 NLM ISO Abbreviation: Breast Cancer Res Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Transcriptomic deconvolution reveals prognostic immune signatures and immunotherapy-responsive subtypes in male breast cancer.
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  Data: <searchLink fieldCode="AU" term="%22Silvestri+V%22">Silvestri V</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Valentini+V%22">Valentini V</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bucalo+A%22">Bucalo A</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Porzio+V%22">Porzio V</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Scafetta+G%22">Scafetta G</searchLink>; Translational Oncology Research Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cerbelli+B%22">Cerbelli B</searchLink>; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Zanna+I%22">Zanna I</searchLink>; Cancer Risk Factors and Lifestyle Epidemiology Unit, Institute for cancer research, prevention and clinical network (ISPRO), Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Bianchi+S%22">Bianchi S</searchLink>; Department of Health Sciences, Division of Pathological Anatomy, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Tibiletti+MG%22">Tibiletti MG</searchLink>; Hereditary Cancer Research Center, University of Insubria, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Carnevali+I%22">Carnevali I</searchLink>; SSD Laboratorio Specialistico Genetica Medica Citogenetica e Genetica Molecolare, ASST Settelaghi Varese, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Calistri+D%22">Calistri D</searchLink>; Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori' IRCCS, Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Arcangeli+V%22">Arcangeli V</searchLink>; Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori' IRCCS, Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Zampiga+V%22">Zampiga V</searchLink>; Istituto Romagnolo per lo Studio dei Tumori 'Dino Amadori' IRCCS, Meldola, Italy.<br /><searchLink fieldCode="AU" term="%22Gasparini+E%22">Gasparini E</searchLink>; Medical Oncology, AUSL- IRCCS Reggio Emilia, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Cortesi+L%22">Cortesi L</searchLink>; Medical Oncology, AUSL- IRCCS Reggio Emilia, Reggio Emilia, Italy.; Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Giannini+G%22">Giannini G</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Capalbo+C%22">Capalbo C</searchLink>; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, Rende, Italy.; Oncology Unit, Annunziata Hospital Cosenza, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Fox+SB%22">Fox SB</searchLink>; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology and Collaborative Centre of Cancer Genomic Medicine, University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Masala+G%22">Masala G</searchLink>; Clinical Epidemiology Unit, Institute for cancer research, prevention and clinical network (ISPRO), Florence, Italy.<br /><searchLink fieldCode="AU" term="%22Mezi+S%22">Mezi S</searchLink>; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22d'Amati+G%22">d'Amati G</searchLink>; Department of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ottini+L%22">Ottini L</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Rome, Italy. laura.ottini@uniroma1.it.
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  Data: <searchLink fieldCode="JN" term="%22100927353%22">Breast cancer research : BCR</searchLink> [Breast Cancer Res] 2026 Apr 07; Vol. 28 (1). <i>Date of Electronic Publication: </i>2026 Apr 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central+Ltd%22">BioMed Central Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100927353 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1465-542X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214655411%22">14655411 </searchLink><i>NLM ISO Abbreviation: </i>Breast Cancer Res <i>Subsets: </i>MEDLINE; In Process
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              Text: 2026 Apr 07
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