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Relative impact of multidomain lifestyle interventions on deficit accumulation frailty over 24 months in the U.S. POINTER trial.

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Title: Relative impact of multidomain lifestyle interventions on deficit accumulation frailty over 24 months in the U.S. POINTER trial.
Authors: Espeland MA; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.; Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States., Olson K; Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, The Miriam Hospital, Providence, Rhode Island, United States., Tangney CC; Department of Clinical Nutrition, Rush University Medical Center, Chicago, Illinois, United States., Gitelman DR; Advocate Aurora Health, Advocate Memory Center and the Advocate Aurora Research Institute, Downers Grove, Advocate Lutheran General Hospital, Park Ridge, Illinois, United States., Cleveland M; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States., Thro AA; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States., Demesie YN; Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States., Snyder HM; Medical and Scientific Relations, Alzheimer's Association, Chicago, Illinois, United States., Whitmer RA; Department of Public Health Sciences, University of California Davis, Sacramento, California, United States., Desai P; Department of Clinical Nutrition, Rush University Medical Center, Chicago, Illinois, United States., Alam R; Department of Public Health Sciences, University of California Davis, Sacramento, California, United States., Crivelli L; Department of Cognitive Neurology, Fleni, Buenos Aires, Argentina., Holland TM; Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States., Preissle O; Alzheimer's Association, Chicago, Illinois, United States., Raman R; Alzheimer's Therapeutic Research Institute, University of Southern California, San Diego, California, United States., York MK; Department of Neurology, Baylor College of Medicine, Houston, Texas, United States., Baker LD; Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States.
Corporate Authors: U.S. POINTER Study Group
Source: The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2026 Apr 07; Vol. 81 (5).
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: published on behalf of the Gerontological Society of America by Oxford University Press Country of Publication: United States NLM ID: 9502837 Publication Model: Print Cited Medium: Internet ISSN: 1758-535X (Electronic) Linking ISSN: 10795006 NLM ISO Abbreviation: J Gerontol A Biol Sci Med Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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