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Elucidating the role of YlMDH2 in temperature-dependent mannitol biosynthesis in Yarrowia lipolytica via integrative multi-omics and structural analysis.

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Title: Elucidating the role of YlMDH2 in temperature-dependent mannitol biosynthesis in Yarrowia lipolytica via integrative multi-omics and structural analysis.
Authors: Iqbal MS; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Xu S; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Zhang Y; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Ji L; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China., Alzahrani KJ; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia., Alsharif KF; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia., Alzahrani FM; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia., Bogale A; Department of Plant science, College of Agriculture and environmental sciences, BahirDar University, P.O.Box 5501, BahirDar, Ethiopia. abebebogaleeth@gmail.com., Cheng H; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China. chrqrq@sjtu.edu.cn.
Source: International microbiology : the official journal of the Spanish Society for Microbiology [Int Microbiol] 2026 Apr 09. Date of Electronic Publication: 2026 Apr 09.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Switzerland NLM ID: 9816585 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-1905 (Electronic) Linking ISSN: 11396709 NLM ISO Abbreviation: Int Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Iqbal+MS%22">Iqbal MS</searchLink>; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Xu+S%22">Xu S</searchLink>; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Ji+L%22">Ji L</searchLink>; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Alzahrani+KJ%22">Alzahrani KJ</searchLink>; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alsharif+KF%22">Alsharif KF</searchLink>; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alzahrani+FM%22">Alzahrani FM</searchLink>; Department of Clinical Laboratories Sciences, College of Applied Medical Sciences, Taif University, P.O. Box 11099, Taif, 21944, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Bogale+A%22">Bogale A</searchLink>; Department of Plant science, College of Agriculture and environmental sciences, BahirDar University, P.O.Box 5501, BahirDar, Ethiopia. abebebogaleeth@gmail.com.<br /><searchLink fieldCode="AU" term="%22Cheng+H%22">Cheng H</searchLink>; State Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China. chrqrq@sjtu.edu.cn.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9816585 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1618-1905 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211396709%22">11396709 </searchLink><i>NLM ISO Abbreviation: </i>Int Microbiol <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10123-026-00820-5
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              Text: 2026 Apr 09
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