Machine learning-based clustering differentiates bilateral hepatocellular carcinoma characteristics and prognosis.

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Title: Machine learning-based clustering differentiates bilateral hepatocellular carcinoma characteristics and prognosis.
Authors: Endo Y; Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH; Division of Transplant Surgery, University of Rochester Medical Center, Rochester, NY., Kawashima J; Department of Surgery, Yokohama City University School of Medicine, Yokohama, Japan., Chatzipanagiotou O; Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH., Woldesenbet S; Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH., Aucejo F; Department of Hepato-pancreatobiliary and Liver Transplant Surgery, Cleveland Clinic Foundation, Cleveland, OH., Marques HP; Department of Surgery, Curry Cabral Hospital, Lisbon, Portugal., Lam V; Department of Surgery, Westmead Hospital, Sydney, NSW, Australia., Lesurtel M; Department of Hepatobiliopancreatic Surgery, APHP, Beaujon Hospital, Clichy, France., Popescu I; Department of Surgery, Fundeni Clinical Institute, Bucharest, Romania., Weiss M; Department of Surgery, Northwell Health Cancer Institute, New Hyde Park, NY., Martel G; Department of Surgery, University of Ottawa, Ottawa, ON, Canada., Poultsides GA; Department of Surgery, Stanford University, Stanford, CA., Ruzzenente A; Department of Surgery, University of Verona, Verona, Italy., Endo I; Department of Surgery, Yokohama City University School of Medicine, Yokohama, Japan., Gleisner A; Department of Surgery, University of Colorado, Denver, CO., Shen F; Department of Hepatic Surgery IV, the Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China., Pawlik TM; Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH. Electronic address: Tim.Pawlik@osumc.edu.
Source: Surgery [Surgery] 2026 Jun; Vol. 194, pp. 110186. Date of Electronic Publication: 2026 Apr 08.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 0417347 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-7361 (Electronic) Linking ISSN: 00396060 NLM ISO Abbreviation: Surgery Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Machine learning-based clustering differentiates bilateral hepatocellular carcinoma characteristics and prognosis.
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  Data: <searchLink fieldCode="AU" term="%22Endo+Y%22">Endo Y</searchLink>; Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH; Division of Transplant Surgery, University of Rochester Medical Center, Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Kawashima+J%22">Kawashima J</searchLink>; Department of Surgery, Yokohama City University School of Medicine, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Chatzipanagiotou+O%22">Chatzipanagiotou O</searchLink>; Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH.<br /><searchLink fieldCode="AU" term="%22Woldesenbet+S%22">Woldesenbet S</searchLink>; Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH.<br /><searchLink fieldCode="AU" term="%22Aucejo+F%22">Aucejo F</searchLink>; Department of Hepato-pancreatobiliary and Liver Transplant Surgery, Cleveland Clinic Foundation, Cleveland, OH.<br /><searchLink fieldCode="AU" term="%22Marques+HP%22">Marques HP</searchLink>; Department of Surgery, Curry Cabral Hospital, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Lam+V%22">Lam V</searchLink>; Department of Surgery, Westmead Hospital, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Lesurtel+M%22">Lesurtel M</searchLink>; Department of Hepatobiliopancreatic Surgery, APHP, Beaujon Hospital, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Popescu+I%22">Popescu I</searchLink>; Department of Surgery, Fundeni Clinical Institute, Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Weiss+M%22">Weiss M</searchLink>; Department of Surgery, Northwell Health Cancer Institute, New Hyde Park, NY.<br /><searchLink fieldCode="AU" term="%22Martel+G%22">Martel G</searchLink>; Department of Surgery, University of Ottawa, Ottawa, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Poultsides+GA%22">Poultsides GA</searchLink>; Department of Surgery, Stanford University, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Ruzzenente+A%22">Ruzzenente A</searchLink>; Department of Surgery, University of Verona, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Endo+I%22">Endo I</searchLink>; Department of Surgery, Yokohama City University School of Medicine, Yokohama, Japan.<br /><searchLink fieldCode="AU" term="%22Gleisner+A%22">Gleisner A</searchLink>; Department of Surgery, University of Colorado, Denver, CO.<br /><searchLink fieldCode="AU" term="%22Shen+F%22">Shen F</searchLink>; Department of Hepatic Surgery IV, the Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Pawlik+TM%22">Pawlik TM</searchLink>; Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, OH. Electronic address: Tim.Pawlik@osumc.edu.
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  Data: <searchLink fieldCode="JN" term="%220417347%22">Surgery</searchLink> [Surgery] 2026 Jun; Vol. 194, pp. 110186. <i>Date of Electronic Publication: </i>2026 Apr 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mosby%22">Mosby </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0417347 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-7361 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200396060%22">00396060 </searchLink><i>NLM ISO Abbreviation: </i>Surgery <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.surg.2026.110186
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        Text: English
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              Text: 2026 Jun
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