High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with type I IFN autoantibodies.
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| Title: | High risk of hypoxemic COVID-19 pneumonia in myasthenia gravis patients with type I IFN autoantibodies. |
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| Authors: | Gervais A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU., Marchal A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU., Maillard A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU., Le Voyer T; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU., Rosain J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, AP-HP, 75015 Paris, France, EU., Philipot Q; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU., Bizien L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU., Peel J; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA., Cederholm A; Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala 75237, Sweden, EU., Migaud M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU., Pons S; Joint Research Unit Civil Hospices of Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France., Saker K; Joint Research Unit Civil Hospices of Lyon-bioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France., Laforet P; Neurology Department, Nord/Est/ Île-de-France Neuromuscular Reference Center, Raymond-Poincaré Teaching Hospital, AP-HP, Garches, France, EU.; INSERM U1179, END-ICAP, Versailles-Saint- Quentin-en-Yvelines University, Université Paris Saclay, Montigny-le-Bretonneux, France, EU., Aubart M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; Department of Pediatric Neurology, Necker Hospital for Sick Children, Paris Cité University, Paris, France, EU., Gitiaux C; Department of Pediatric Neurology, Necker Hospital for Sick Children, Paris Cité University, Paris, France, EU., Biggs C; Department of Pediatrics, British Columbia Children's Hospital, The University of British Columbia, Vancouver, BC, Canada., Leon Lopez R; Hospital Universitario Reina Sofía, Cordoba, Spain., Souvannanorath S; Reference Center for Neuromuscular Diseases, Henri Mondor University Hospital, Assistance Publique - Hôpitaux de Paris (AP-HP), Créteil, France, EU., Tard C; CHU de Lille, Inserm U1171, Reference Center for Neuromuscular Disorders Nord/Est/Île-de-France, Lille, France, EU., Nadaj Pakleza A; Neurology Department, Reference Center for Neuromuscular Diseases 'Nord-Est-Ile de France', University Hospitals of Strasbourg, and ERN EURO-NMD, Strasbourg, France, EU., Grapperon AM; Reference Center for Neuromuscular Diseases and ALS, ERN EURO-NMD, La Timone University Hospital, Aix-Marseille University, Marseille, France, EU., Heming N; Laboratory of Infection & Inflammation-U1173, School of Medicine, INSERM, University Versailles Saint Quentin-University Paris Saclay, Garches, France, EU.; FHU SEPSIS (Saclay and Paris Seine Nord Endeavour to PerSonalize Interventions for Sepsis), Garches, France, EU.; RHU RECORDS (Rapid rEcognition of CORticosteroiD resistant or sensitive Sepsis), Garches, France, EU.; Institut Hospitalo Universitaire PROMETHEUS, Garches, France., Annane D; Laboratory of Infection & Inflammation-U1173, School of Medicine, INSERM, University Versailles Saint Quentin-University Paris Saclay, Garches, France, EU.; FHU SEPSIS (Saclay and Paris Seine Nord Endeavour to PerSonalize Interventions for Sepsis), Garches, France, EU.; RHU RECORDS (Rapid rEcognition of CORticosteroiD resistant or sensitive Sepsis), Garches, France, EU.; Institut Hospitalo Universitaire PROMETHEUS, Garches, France., Verschueren A; Reference Center for Neuromuscular Diseases and ALS, ERN EURO-NMD, La Timone University Hospital, Aix-Marseille University, Marseille, France, EU., Attarian S; Reference Center for Neuromuscular Diseases and ALS, ERN EURO-NMD, La Timone University Hospital, Aix-Marseille University, Marseille, France, EU., Bigaut K; Neurology Department, Reference Center for Neuromuscular Diseases 'Nord-Est-Ile de France', University Hospitals of Strasbourg, and ERN EURO-NMD, Strasbourg, France, EU., Hankiewicz K; Department of Neurology, Hôpital Pierre Delafontaine, Centre Hospitalier de Saint-Denis, F-93200 Saint-Denis, France., Kouton L; Reference Center for Neuromuscular Diseases and ALS, ERN EURO-NMD, La Timone University Hospital, Aix-Marseille University, Marseille, France, EU., Villar-Quiles RN; Centre de Référence des Maladies Neuromusculaires Nord / Est / Ile-de-France. Sorbonne Université Centre de Recherche en Myologie - UMRS974 Groupe Hospitalier Pitié-Salpêtrière, Paris, France, EU., Cauquil C; Inserm U 1195, Service de Neurologie, CRMR Neuropathies Amyloïdes et Autres Neuropathies Périphériques Rares, DMU Neurosciences, Paris Saclay University, CHU Bicêtre, AP-HP, NNERf FILNEMUS, Le Kremlin-Bicêtre, France, EU., Fleury MC; Neurology Department, Reference Center for Neuromuscular Diseases 'Nord-Est-Ile de France', University Hospitals of Strasbourg, and ERN EURO-NMD, Strasbourg, France, EU., Rocher E; Neurology Department, Reference Center for Neuromuscular Diseases 'Nord-Est-Ile de France', University Hospitals of Strasbourg, and ERN EURO-NMD, Strasbourg, France, EU., Nicolas G; Neurology Department, Nord/Est/ Île-de-France Neuromuscular Reference Center, Raymond-Poincaré Teaching Hospital, AP-HP, Garches, France, EU.; INSERM U1179, END-ICAP, Versailles-Saint- Quentin-en-Yvelines University, Université Paris Saclay, Montigny-le-Bretonneux, France, EU., de Paula Estephan E; Department of Neurology, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil.; Faculdade de Medicina de São José do Rio Preto, Departamento de Ciências Neurológicas, Psiquiatria e Psicologia Médica, São José do Rio Preto SP, Brazil., da Penha Ananias Morita M; Faculdade de Medicina de São José do Rio Preto, Departamento de Ciências Neurológicas, Psiquiatria e Psicologia Médica, São José do Rio Preto SP, Brazil., Zanoteli E; Department of Neurology, Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil., Saied Z; National Institute Mongi Ben Hamida of Neurology - Faculty of Medicine Tunis El Manar University - 1007 - Tunis - Tunisia., Rachdi A; National Institute Mongi Ben Hamida of Neurology - Faculty of Medicine Tunis El Manar University - 1007 - Tunis - Tunisia., Rim A; Department of Molecular Neurobiology and Neuropathology, National Institute Mongi Ben Hamida of Neurology - 1007 - Tunis- Tunisia., Belal S; National Institute Mongi Ben Hamida of Neurology - Faculty of Medicine Tunis El Manar University - 1007 - Tunis - Tunisia., Ben Sassi S; National Institute Mongi Ben Hamida of Neurology - Faculty of Medicine Tunis El Manar University - 1007 - Tunis - Tunisia., Hübers A; Department of Neurology, University Hospital Düsseldorf, 40223 Düsseldorf, Germany, EU., Faure E; Department of Neurology, Sorbonne University, AP-HP, University Hospitals - Pitié-Salpétrière Charles Foix, Paris, France, EU.; Institut du Thorax Curie Montsouris, Institut Curie, Paris, France, EU., Desguerre I; Department of Pediatric Neurology, Necker Hospital for Sick Children, Paris Cité University, Paris, France, EU., Basse C; Institut du Thorax Curie Montsouris, Institut Curie, Paris, France, EU.; UVSQ, UFR Simone Veil, Paris Saclay University, Versailles, France, EU., Girard N; Institut du Thorax Curie Montsouris, Institut Curie, Paris, France, EU.; UVSQ, UFR Simone Veil, Paris Saclay University, Versailles, France, EU., Béziat V; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA., Pan-Hammarström Q; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden, EU., Hammarström L; Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden, EU., Bodansky A; Department of Pediatric Critical Care Medicine, University of California, San Francisco, San Francisco, USA., Parent AV; Department of Pediatric Critical Care Medicine, University of California, San Francisco, San Francisco, USA., Anderson MS; Diabetes Center, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA., DeRisi JL; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.; Chan Zuckerberg Biohub, San Francisco, CA 94158, USA. Ǹeurological Intensive Care Medicine, La Pitié-Salpétrière Hospital, AP-HP, Paris, France, EU., Demeret S; Sorbonne University, INSERM, Institute of Myology, Center of Research in Myology, UMRS 974, F-75013 Paris, France., Truffault F; Sorbonne University, INSERM, Institute of Myology, Center of Research in Myology, UMRS 974, F-75013 Paris, France., Fort R; Department of Anesthesia and Intensive Care Unit, Lyon Sud Hospital, Hospices Civils de Lyon, 69149 Pierre Bénite, France., Ader F; Service de Maladies Infectieuses et Tropicales, Hospices Civils de Lyon, Hôpital de la Croix Rousse, Lyon, France., Wallet F; Médecine Intensive Réanimation, Centre Hospitalier Universitaire Lyon Sud, Hospices Civiles de Lyon, Lyon, France., Abel L; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA., Molina T; Paris Cité University, Imagine Institute, Paris, France, EU.; Department of Pathology, Necker Hospital for Sick Children, Paris, France, EU., Alyanakian MA; Necker Biological Resource Center and Immunology Laboratory, Necker Hospital for Sick Children, AP-HP, Paris, France., Le Panse R; Sorbonne University, INSERM, Institute of Myology, Center of Research in Myology, UMRS 974, F-75013 Paris, France., Solé G; Department of Neurology and Neuromuscular Disorders, Reference Center for Neuromuscular Disorders AOC, University Hospitals of Bordeaux (Pellegrin University Hospital), place Amélie-Raba-Léon, Bordeaux, France, EU.; University of Bordeaux, Bordeaux, France, EU., Cobat A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA., Landegren N; Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala 75237, Sweden, EU., Casanova JL; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Howard Hughes Medical Institute, New York, NY, USA.; Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France, EU., Puel A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA., Bastard P; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA.; Pediatric Hematology-Immunology and Rheumatology Unit, Necker Hospital for Sick Children, AP-HP, Paris, France, EU., Jouanguy E; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, Paris, France, EU.; Paris Cité University, Imagine Institute, Paris, France, EU.; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA. |
| Source: | MedRxiv : the preprint server for health sciences [medRxiv] 2026 Apr 02. Date of Electronic Publication: 2026 Apr 02. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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