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Omega-3 fatty acid DHA induces ferroptosis in colorectal cancer patient-derived organoids and drug-tolerant cells.

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Title: Omega-3 fatty acid DHA induces ferroptosis in colorectal cancer patient-derived organoids and drug-tolerant cells.
Authors: di Blasio L; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Vara-Messler M; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.; Sanofi Belgium, Zwijnaarde, Belgium., Peracino B; Department of Clinical and Biological Sciences, University of Torino, Torino, Italy., Masti E; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Cepas-López V; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Trusolino L; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Puliafito A; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Bertotti A; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Monica V; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Primo L; Department of Oncology, University of Torino, Torino, Italy. luca.primo@unito.it.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy. luca.primo@unito.it.
Source: Cell death & disease [Cell Death Dis] 2026 Apr 11; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Omega-3 fatty acid DHA induces ferroptosis in colorectal cancer patient-derived organoids and drug-tolerant cells.
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  Data: <searchLink fieldCode="AU" term="%22di+Blasio+L%22">di Blasio L</searchLink>; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.<br /><searchLink fieldCode="AU" term="%22Vara-Messler+M%22">Vara-Messler M</searchLink>; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.; Sanofi Belgium, Zwijnaarde, Belgium.<br /><searchLink fieldCode="AU" term="%22Peracino+B%22">Peracino B</searchLink>; Department of Clinical and Biological Sciences, University of Torino, Torino, Italy.<br /><searchLink fieldCode="AU" term="%22Masti+E%22">Masti E</searchLink>; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.<br /><searchLink fieldCode="AU" term="%22Cepas-López+V%22">Cepas-López V</searchLink>; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.<br /><searchLink fieldCode="AU" term="%22Trusolino+L%22">Trusolino L</searchLink>; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.<br /><searchLink fieldCode="AU" term="%22Puliafito+A%22">Puliafito A</searchLink>; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.<br /><searchLink fieldCode="AU" term="%22Bertotti+A%22">Bertotti A</searchLink>; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.<br /><searchLink fieldCode="AU" term="%22Monica+V%22">Monica V</searchLink>; Department of Oncology, University of Torino, Torino, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy.<br /><searchLink fieldCode="AU" term="%22Primo+L%22">Primo L</searchLink>; Department of Oncology, University of Torino, Torino, Italy. luca.primo@unito.it.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy. luca.primo@unito.it.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Apr 11; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Apr 11.
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              Text: 2026 Apr 11
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