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Immune dysregulation in prolonged Long-COVID: lymphocytes emerge as key mediators of persistent inflammation, exhaustion and cytotoxicity.

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Title: Immune dysregulation in prolonged Long-COVID: lymphocytes emerge as key mediators of persistent inflammation, exhaustion and cytotoxicity.
Authors: Springe ML; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Vaivode K; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Saksis R; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Vainšeļbauma NM; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Ansone L; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Brīvība M; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Niedra H; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia., Rovite V; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia. vita.rovite@biomed.lu.lv.
Source: Journal of translational medicine [J Transl Med] 2026 Apr 11; Vol. 24 (1). Date of Electronic Publication: 2026 Apr 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Immune dysregulation in prolonged Long-COVID: lymphocytes emerge as key mediators of persistent inflammation, exhaustion and cytotoxicity.
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  Data: <searchLink fieldCode="AU" term="%22Springe+ML%22">Springe ML</searchLink>; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia.<br /><searchLink fieldCode="AU" term="%22Vaivode+K%22">Vaivode K</searchLink>; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia.<br /><searchLink fieldCode="AU" term="%22Saksis+R%22">Saksis R</searchLink>; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia.<br /><searchLink fieldCode="AU" term="%22Vainšeļbauma+NM%22">Vainšeļbauma NM</searchLink>; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia.<br /><searchLink fieldCode="AU" term="%22Ansone+L%22">Ansone L</searchLink>; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia.<br /><searchLink fieldCode="AU" term="%22Brīvība+M%22">Brīvība M</searchLink>; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia.<br /><searchLink fieldCode="AU" term="%22Niedra+H%22">Niedra H</searchLink>; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia.<br /><searchLink fieldCode="AU" term="%22Rovite+V%22">Rovite V</searchLink>; Latvian Biomedical Research and Study Centre, Riga, LV-1067, Latvia. vita.rovite@biomed.lu.lv.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Apr 11; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Apr 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12967-026-08081-6
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              Text: 2026 Apr 11
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