Experimental and computational methods for allelic imbalance analysis from single-nucleus RNA-seq data.
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| Title: | Experimental and computational methods for allelic imbalance analysis from single-nucleus RNA-seq data. |
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| Authors: | Simmons SK; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA. seankenneths@gmail.com.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. seankenneths@gmail.com.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. seankenneths@gmail.com., Adiconis X; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Haywood N; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Parker J; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Stephen & Denise Adams Center for Parkinson's Disease Research of Yale School of Medicine, New Haven, CT, 06510, USA., Lin Z; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Stephen & Denise Adams Center for Parkinson's Disease Research of Yale School of Medicine, New Haven, CT, 06510, USA., Liao Z; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Precision Neurology Program of Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Tuncali I; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Precision Neurology Program of Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Shin A; Broad Clinical Labs, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Jagadeesh K; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Gosik K; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Gatzen M; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Smith JT; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., El Kodsi DN; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Precision Neurology Program of Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Kuras Y; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Precision Neurology Program of Brigham & Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Baecher-Allan C; Dept. of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Serrano GE; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Banner Sun Health Research Institute, Sun City, AZ, 85351, USA., Beach TG; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Banner Sun Health Research Institute, Sun City, AZ, 85351, USA., Garimella K; Data Sciences Platform, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Al'Khafaji AM; Broad Clinical Labs, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Present Address: Genentech, South San Francisco, CA, 94080, USA., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Present Address: Genentech, South San Francisco, CA, 94080, USA., Dong X; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Stephen & Denise Adams Center for Parkinson's Disease Research of Yale School of Medicine, New Haven, CT, 06510, USA., Scherzer CR; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Stephen & Denise Adams Center for Parkinson's Disease Research of Yale School of Medicine, New Haven, CT, 06510, USA., Levin JZ; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, 20815, USA.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. |
| Source: | Genome biology [Genome Biol] 2026 Apr 11; Vol. 27 (1). Date of Electronic Publication: 2026 Apr 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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