Cytotoxic Edema and Intra-parenchymal Hemorrhage: A Mediated Pathway to Mortality and Functional Outcome in Cerebral Venous Sinus Thrombosis- A sub-analysis of the CLOT-VENUS Registry.

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Title: Cytotoxic Edema and Intra-parenchymal Hemorrhage: A Mediated Pathway to Mortality and Functional Outcome in Cerebral Venous Sinus Thrombosis- A sub-analysis of the CLOT-VENUS Registry.
Authors: Abdelhakim N; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA., Galecio-Castillo M; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA., Kalakoti P; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA., Cruz-Criollo L; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA., Rodriguez-Calienes A; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.; Universidad Científica del Sur, Lima, Perú., Brito A; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA., Cespedes J; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA., Shaban A; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA., Venkatesan A; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA., Nigenda VC; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México., Pompa AAM; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México., Mohr NM; Departments of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA.; Division of Critical Care, Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City, IA, USA., Pereda-Castillo A; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México., Peregrino KE; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México., Ruvalcaba HV; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México., Smith BJ; Department of Biostatistics, University of Iowa, Iowa City, IA, USA., Torner JC; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA., Barboza MA; Department of Neuroscience, Hospital Dr. Rafael A. Calderon Guardia, San Jose, Costa Rica., Arauz A; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México., Ortega-Gutierrez S; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA. santy-ortega@uiowa.edu.; Department of Neurosurgery, University of Iowa Health Care, Iowa City, IA, USA. santy-ortega@uiowa.edu.; Department of Radiology, University of Iowa Health Care, Iowa City, IA, USA. santy-ortega@uiowa.edu.
Source: Translational stroke research [Transl Stroke Res] 2026 Apr 14; Vol. 17 (2). Date of Electronic Publication: 2026 Apr 14.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101517297 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-601X (Electronic) Linking ISSN: 18684483 NLM ISO Abbreviation: Transl Stroke Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Abdelhakim+N%22">Abdelhakim N</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Galecio-Castillo+M%22">Galecio-Castillo M</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Kalakoti+P%22">Kalakoti P</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Cruz-Criollo+L%22">Cruz-Criollo L</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Calienes+A%22">Rodriguez-Calienes A</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.; Universidad Científica del Sur, Lima, Perú.<br /><searchLink fieldCode="AU" term="%22Brito+A%22">Brito A</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Cespedes+J%22">Cespedes J</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Shaban+A%22">Shaban A</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Venkatesan+A%22">Venkatesan A</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Nigenda+VC%22">Nigenda VC</searchLink>; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México.<br /><searchLink fieldCode="AU" term="%22Pompa+AAM%22">Pompa AAM</searchLink>; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México.<br /><searchLink fieldCode="AU" term="%22Mohr+NM%22">Mohr NM</searchLink>; Departments of Emergency Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA.; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA.; Division of Critical Care, Department of Anesthesia, University of Iowa Carver College of Medicine, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Pereda-Castillo+A%22">Pereda-Castillo A</searchLink>; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México.<br /><searchLink fieldCode="AU" term="%22Peregrino+KE%22">Peregrino KE</searchLink>; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México.<br /><searchLink fieldCode="AU" term="%22Ruvalcaba+HV%22">Ruvalcaba HV</searchLink>; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México.<br /><searchLink fieldCode="AU" term="%22Smith+BJ%22">Smith BJ</searchLink>; Department of Biostatistics, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Torner+JC%22">Torner JC</searchLink>; Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA.<br /><searchLink fieldCode="AU" term="%22Barboza+MA%22">Barboza MA</searchLink>; Department of Neuroscience, Hospital Dr. Rafael A. Calderon Guardia, San Jose, Costa Rica.<br /><searchLink fieldCode="AU" term="%22Arauz+A%22">Arauz A</searchLink>; Instituto Nacional de Neurologia y Neurocirugía Manuel Velasco Suárez, México City, México.<br /><searchLink fieldCode="AU" term="%22Ortega-Gutierrez+S%22">Ortega-Gutierrez S</searchLink>; Department of Neurology, University of Iowa Health Care, Iowa City, IA, USA. santy-ortega@uiowa.edu.; Department of Neurosurgery, University of Iowa Health Care, Iowa City, IA, USA. santy-ortega@uiowa.edu.; Department of Radiology, University of Iowa Health Care, Iowa City, IA, USA. santy-ortega@uiowa.edu.
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  Data: <searchLink fieldCode="JN" term="%22101517297%22">Translational stroke research</searchLink> [Transl Stroke Res] 2026 Apr 14; Vol. 17 (2). <i>Date of Electronic Publication: </i>2026 Apr 14.
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