Schisandrol B protects against lithocholic acid-induced cholestatic liver injury in mice through mitochondrial biogenesis.

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Title: Schisandrol B protects against lithocholic acid-induced cholestatic liver injury in mice through mitochondrial biogenesis.
Authors: Yang X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023# Shatai South Road, Baiyun District, Guangzhou, 510515, People's Republic of China., Liang H; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China., Li X; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023# Shatai South Road, Baiyun District, Guangzhou, 510515, People's Republic of China., Tian J; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China., Fan S; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023# Shatai South Road, Baiyun District, Guangzhou, 510515, People's Republic of China., Huang M; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China., Wan J; State Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China., Zuo Z; School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, China., Guo H; Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co., Ltd., Guangzhou, 510515, Guangdong, China. taylorghb@qq.com., Bi H; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023# Shatai South Road, Baiyun District, Guangzhou, 510515, People's Republic of China. bihchang@smu.edu.cn.
Source: Chinese medicine [Chin Med] 2026 Apr 14; Vol. 21 (1). Date of Electronic Publication: 2026 Apr 14.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265109 Publication Model: Electronic Cited Medium: Print ISSN: 1749-8546 (Print) Linking ISSN: 17498546 NLM ISO Abbreviation: Chin Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Schisandrol B protects against lithocholic acid-induced cholestatic liver injury in mice through mitochondrial biogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023# Shatai South Road, Baiyun District, Guangzhou, 510515, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liang+H%22">Liang H</searchLink>; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023# Shatai South Road, Baiyun District, Guangzhou, 510515, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Tian+J%22">Tian J</searchLink>; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.<br /><searchLink fieldCode="AU" term="%22Fan+S%22">Fan S</searchLink>; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023# Shatai South Road, Baiyun District, Guangzhou, 510515, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, 510006, China.<br /><searchLink fieldCode="AU" term="%22Wan+J%22">Wan J</searchLink>; State Key Laboratory of Mechanism and Quality of Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.<br /><searchLink fieldCode="AU" term="%22Zuo+Z%22">Zuo Z</searchLink>; School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, China.<br /><searchLink fieldCode="AU" term="%22Guo+H%22">Guo H</searchLink>; Hutchison Whampoa Guangzhou Baiyunshan Chinese Medicine Co., Ltd., Guangzhou, 510515, Guangdong, China. taylorghb@qq.com.<br /><searchLink fieldCode="AU" term="%22Bi+H%22">Bi H</searchLink>; NMPA Key Laboratory for Research and Evaluation of Drug Metabolism & Guangdong Provincial Key Laboratory of New Drug Screening & Guangdong-Hongkong-Macao Joint Laboratory for New Drug Screening, School of Pharmaceutical Sciences, Southern Medical University, 1023# Shatai South Road, Baiyun District, Guangzhou, 510515, People's Republic of China. bihchang@smu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101265109%22">Chinese medicine</searchLink> [Chin Med] 2026 Apr 14; Vol. 21 (1). <i>Date of Electronic Publication: </i>2026 Apr 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101265109 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1749-8546 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217498546%22">17498546 </searchLink><i>NLM ISO Abbreviation: </i>Chin Med <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1186/s13020-026-01342-y
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            – D: 14
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              Text: 2026 Apr 14
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