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Bitter Taste Signalling via TAS2R43 Enhances Temozolomide Efficacy in Glioblastoma Cells.

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Title: Bitter Taste Signalling via TAS2R43 Enhances Temozolomide Efficacy in Glioblastoma Cells.
Authors: Costa AR; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal., Duarte AC; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal., Gonçalves I; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal., Preissner R; Institute of Physiology and Science-IT, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115 Berlin, Germany., Cascalheira JF; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.; RISE-Health, Department of Chemistry, Faculty of Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal., Marcelino H; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.; RISE-Health, Department of Chemistry, Faculty of Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal., Santos CRA; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Apr 03; Vol. 27 (7). Date of Electronic Publication: 2026 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Bitter Taste Signalling via TAS2R43 Enhances Temozolomide Efficacy in Glioblastoma Cells.
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  Data: <searchLink fieldCode="AU" term="%22Costa+AR%22">Costa AR</searchLink>; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.<br /><searchLink fieldCode="AU" term="%22Duarte+AC%22">Duarte AC</searchLink>; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.<br /><searchLink fieldCode="AU" term="%22Gonçalves+I%22">Gonçalves I</searchLink>; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.<br /><searchLink fieldCode="AU" term="%22Preissner+R%22">Preissner R</searchLink>; Institute of Physiology and Science-IT, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Philippstrasse 12, 10115 Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Cascalheira+JF%22">Cascalheira JF</searchLink>; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.; RISE-Health, Department of Chemistry, Faculty of Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.<br /><searchLink fieldCode="AU" term="%22Marcelino+H%22">Marcelino H</searchLink>; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.; RISE-Health, Department of Chemistry, Faculty of Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.<br /><searchLink fieldCode="AU" term="%22Santos+CRA%22">Santos CRA</searchLink>; RISE-Health, Department of Medical Sciences, Faculty of Health Sciences, University of Beira Interior, 6200-506 Covilhã, Portugal.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2026 Apr 03; Vol. 27 (7). <i>Date of Electronic Publication: </i>2026 Apr 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101092791 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1422-0067 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214220067%22">14220067 </searchLink><i>NLM ISO Abbreviation: </i>Int J Mol Sci <i>Subsets: </i>MEDLINE
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        Value: 10.3390/ijms27073262
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      – TitleFull: Bitter Taste Signalling via TAS2R43 Enhances Temozolomide Efficacy in Glioblastoma Cells.
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              Text: 2026 Apr 03
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