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Serum homocysteine, hemoglobin, and Alzheimer's biomarkers involved in the relationship of folate and vitamin B12 with cognitive function: Findings from the Hubei Memory and Aging Cohort Study.

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Title: Serum homocysteine, hemoglobin, and Alzheimer's biomarkers involved in the relationship of folate and vitamin B12 with cognitive function: Findings from the Hubei Memory and Aging Cohort Study.
Authors: Li CX; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Cheng GR; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Liu XC; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Chen M; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Dong H; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Meng H; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Peng YY; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Liu N; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Che JW; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Zhang YY; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Wang ZM; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Zhou W; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Luo Y; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Liu L; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Lu JY; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Liu AQ; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Liu D; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Hu FF; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Xie XY; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Cheng YF; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Wang X; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China., Xu L; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China., Tan W; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China., Zeng Y; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China. Electronic address: zengyan68@wust.edu.cn.
Source: Nutrition research (New York, N.Y.) [Nutr Res] 2026 May; Vol. 149, pp. 178-188. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8303331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0739 (Electronic) Linking ISSN: 02715317 NLM ISO Abbreviation: Nutr Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Serum homocysteine, hemoglobin, and Alzheimer's biomarkers involved in the relationship of folate and vitamin B12 with cognitive function: Findings from the Hubei Memory and Aging Cohort Study.
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  Data: <searchLink fieldCode="AU" term="%22Li+CX%22">Li CX</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Cheng+GR%22">Cheng GR</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liu+XC%22">Liu XC</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Dong+H%22">Dong H</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Meng+H%22">Meng H</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Peng+YY%22">Peng YY</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Che+JW%22">Che JW</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YY%22">Zhang YY</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Wang+ZM%22">Wang ZM</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Zhou+W%22">Zhou W</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Luo+Y%22">Luo Y</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Lu+JY%22">Lu JY</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liu+AQ%22">Liu AQ</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Hu+FF%22">Hu FF</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Xie+XY%22">Xie XY</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Cheng+YF%22">Cheng YF</searchLink>; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Xu+L%22">Xu L</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Tan+W%22">Tan W</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Zeng+Y%22">Zeng Y</searchLink>; Geriatric Hospital Affiliated to Wuhan University of Science and Technology, Wuhan, China; Hubei Provincial Clinical Research Center for Alzheimer's Disease, Tian You Hospital, School of Medicine, Wuhan University of Science and Technology, Wuhan, China; Brain Science and Advanced Technology Institute, Wuhan University of Science and Technology, Wuhan, China. Electronic address: zengyan68@wust.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%228303331%22">Nutrition research (New York, N.Y.)</searchLink> [Nutr Res] 2026 May; Vol. 149, pp. 178-188. <i>Date of Electronic Publication: </i>2026 Mar 20.
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