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Severe periodontitis patients with well-controlled type 2 diabetes display a distinct subgingival microbiome with increased Saccharibacteria compared to systemically healthy controls.

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Title: Severe periodontitis patients with well-controlled type 2 diabetes display a distinct subgingival microbiome with increased Saccharibacteria compared to systemically healthy controls.
Authors: Shi S; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China., Wang S; Central Laboratory, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China., Li S; Second Clinical Division, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China., Lu R; Department of Periodontology, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China., Pan S; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China., Chen F; Central Laboratory, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China., He X; Department of Microbiology, American Dental Association Forsyth Institute, Somerville, MA, United States.
Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2026 Mar 30; Vol. 16, pp. 1814983. Date of Electronic Publication: 2026 Mar 30 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
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  Data: Severe periodontitis patients with well-controlled type 2 diabetes display a distinct subgingival microbiome with increased Saccharibacteria compared to systemically healthy controls.
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  Data: <searchLink fieldCode="AU" term="%22Shi+S%22">Shi S</searchLink>; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Central Laboratory, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Second Clinical Division, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Lu+R%22">Lu R</searchLink>; Department of Periodontology, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Pan+S%22">Pan S</searchLink>; Department of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+F%22">Chen F</searchLink>; Central Laboratory, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & National Health Commission Key Laboratory of Digital Stomatology & National Medical Products Administration Key Laboratory for Dental Materials, Beijing, China.<br /><searchLink fieldCode="AU" term="%22He+X%22">He X</searchLink>; Department of Microbiology, American Dental Association Forsyth Institute, Somerville, MA, United States.
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  Data: <searchLink fieldCode="JN" term="%22101585359%22">Frontiers in cellular and infection microbiology</searchLink> [Front Cell Infect Microbiol] 2026 Mar 30; Vol. 16, pp. 1814983. <i>Date of Electronic Publication: </i>2026 Mar 30 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+SA%22">Frontiers Media SA </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101585359 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2235-2988 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222352988%22">22352988 </searchLink><i>NLM ISO Abbreviation: </i>Front Cell Infect Microbiol <i>Subsets: </i>MEDLINE
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        Value: 10.3389/fcimb.2026.1814983
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              Text: 2026 Mar 30
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