Social Disconnection, Genetic Risk, and the Incidence of Degenerative Valvular Heart Disease: A Population-Based Cohort Study.

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Title: Social Disconnection, Genetic Risk, and the Incidence of Degenerative Valvular Heart Disease: A Population-Based Cohort Study.
Authors: Cao C; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Xiangya School of Medicine Central South University Changsha Hunan China.; Libin Cardiovascular Institute of Alberta, University of Calgary, Health Sciences Centre Calgary Alberta Canada.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China., Wei C; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Department of Cardiology, Erasmus MC University Medical Center Rotterdam Rotterdam The Netherlands., Gong W; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China., Yu B; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Research Institute of Blood Lipid and Atherosclerosis Central South University Changsha Hunan China., Fang Z; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Research Institute of Blood Lipid and Atherosclerosis Central South University Changsha Hunan China., Zhou S; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Research Institute of Blood Lipid and Atherosclerosis Central South University Changsha Hunan China., Zhu Z; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Research Institute of Blood Lipid and Atherosclerosis Central South University Changsha Hunan China.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2026 Apr 21; Vol. 15 (8), pp. e045931. Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Social Disconnection, Genetic Risk, and the Incidence of Degenerative Valvular Heart Disease: A Population-Based Cohort Study.
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  Data: <searchLink fieldCode="AU" term="%22Cao+C%22">Cao C</searchLink>; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Xiangya School of Medicine Central South University Changsha Hunan China.; Libin Cardiovascular Institute of Alberta, University of Calgary, Health Sciences Centre Calgary Alberta Canada.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.<br /><searchLink fieldCode="AU" term="%22Wei+C%22">Wei C</searchLink>; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Department of Cardiology, Erasmus MC University Medical Center Rotterdam Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gong+W%22">Gong W</searchLink>; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Research Institute of Blood Lipid and Atherosclerosis Central South University Changsha Hunan China.<br /><searchLink fieldCode="AU" term="%22Fang+Z%22">Fang Z</searchLink>; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Research Institute of Blood Lipid and Atherosclerosis Central South University Changsha Hunan China.<br /><searchLink fieldCode="AU" term="%22Zhou+S%22">Zhou S</searchLink>; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Research Institute of Blood Lipid and Atherosclerosis Central South University Changsha Hunan China.<br /><searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; Department of Cardiovascular Medicine, The Second Xiangya Hospital Central South University Changsha Hunan China.; Key Laboratory of Cardiometabolic Medicine in Hunan Province Changsha Hunan China.; Research Institute of Blood Lipid and Atherosclerosis Central South University Changsha Hunan China.
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  Data: <searchLink fieldCode="JN" term="%22101580524%22">Journal of the American Heart Association</searchLink> [J Am Heart Assoc] 2026 Apr 21; Vol. 15 (8), pp. e045931. <i>Date of Electronic Publication: </i>2026 Apr 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101580524 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2047-9980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220479980%22">20479980 </searchLink><i>NLM ISO Abbreviation: </i>J Am Heart Assoc <i>Subsets: </i>MEDLINE
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        Value: 10.1161/JAHA.125.045931
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        Text: English
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      – TitleFull: Social Disconnection, Genetic Risk, and the Incidence of Degenerative Valvular Heart Disease: A Population-Based Cohort Study.
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            – D: 21
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              Text: 2026 Apr 21
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              Y: 2026
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