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Disuse-Induced Muscle Atrophy and Muscle Weakness From Hospitalization to Spaceflight: Exercise Succeeds in Prevention and Treatment-A Meta-Analysis.

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Title: Disuse-Induced Muscle Atrophy and Muscle Weakness From Hospitalization to Spaceflight: Exercise Succeeds in Prevention and Treatment-A Meta-Analysis.
Authors: Padilha CS; Centre for Healthy Ageing, Biology of Ageing Laboratory, Centenary Institute of Cancer Medicine and Cell Biology, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia.; School of Sport, Exercise and Rehabilitation Science, Faculty of Health, University of Technology Sydney (UTS), Sydney, NSW, Australia.; Exercise and Immunometabolism Research Group, Postgraduation Program in Movement Sciences, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, São Paulo, Brazil., Figueiredo C; Exercise and Immunometabolism Research Group, Postgraduation Program in Movement Sciences, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, São Paulo, Brazil.; Immunometabolism Research Group, Department of Cell Biology and Developmental, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Deminice R; Laboratory of Biochemistry Exercise, Department of Physical Education, Faculty of Physical Education and Sport, State University of Londrina, Londrina, Brazil., Ribeiro AS; Faculty of Sports Sciences and Physical Education, CIPER, University of Coimbra, Coimbra, Portugal., Newton RU; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia., Hart NH; School of Sport, Exercise and Rehabilitation Science, Faculty of Health, University of Technology Sydney (UTS), Sydney, NSW, Australia.; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.; Human Performance Research Centre, INSIGHT Research Institute, Faculty of Health, University of Technology Sydney (UTS), Sydney, NSW, Australia., Rosa-Neto JC; Immunometabolism Research Group, Department of Cell Biology and Developmental, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil., Seelaender M; Cancer Metabolism Research Group, Department of Surgery, LIM26-HC and C2PO, Faculdade de Medicina, CoMeta-HU, University of São Paulo, São Paulo, Brazil., Lira FS; Exercise and Immunometabolism Research Group, Postgraduation Program in Movement Sciences, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, São Paulo, Brazil.; Faculty of Sports Sciences and Physical Education, CIPER, University of Coimbra, Coimbra, Portugal.
Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2026 Apr; Vol. 17 (2), pp. e70259.
Publication Type: Meta-Analysis; Journal Article; Systematic Review; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication Model: Print Cited Medium: Internet ISSN: 2190-6009 (Electronic) Linking ISSN: 21905991 NLM ISO Abbreviation: J Cachexia Sarcopenia Muscle Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Disuse-Induced Muscle Atrophy and Muscle Weakness From Hospitalization to Spaceflight: Exercise Succeeds in Prevention and Treatment-A Meta-Analysis.
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  Data: <searchLink fieldCode="AU" term="%22Padilha+CS%22">Padilha CS</searchLink>; Centre for Healthy Ageing, Biology of Ageing Laboratory, Centenary Institute of Cancer Medicine and Cell Biology, Royal Prince Alfred Hospital, Sydney, NSW, Australia.; Faculty of Medicine and Health, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia.; School of Sport, Exercise and Rehabilitation Science, Faculty of Health, University of Technology Sydney (UTS), Sydney, NSW, Australia.; Exercise and Immunometabolism Research Group, Postgraduation Program in Movement Sciences, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Figueiredo+C%22">Figueiredo C</searchLink>; Exercise and Immunometabolism Research Group, Postgraduation Program in Movement Sciences, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, São Paulo, Brazil.; Immunometabolism Research Group, Department of Cell Biology and Developmental, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Deminice+R%22">Deminice R</searchLink>; Laboratory of Biochemistry Exercise, Department of Physical Education, Faculty of Physical Education and Sport, State University of Londrina, Londrina, Brazil.<br /><searchLink fieldCode="AU" term="%22Ribeiro+AS%22">Ribeiro AS</searchLink>; Faculty of Sports Sciences and Physical Education, CIPER, University of Coimbra, Coimbra, Portugal.<br /><searchLink fieldCode="AU" term="%22Newton+RU%22">Newton RU</searchLink>; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.<br /><searchLink fieldCode="AU" term="%22Hart+NH%22">Hart NH</searchLink>; School of Sport, Exercise and Rehabilitation Science, Faculty of Health, University of Technology Sydney (UTS), Sydney, NSW, Australia.; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.; Human Performance Research Centre, INSIGHT Research Institute, Faculty of Health, University of Technology Sydney (UTS), Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Rosa-Neto+JC%22">Rosa-Neto JC</searchLink>; Immunometabolism Research Group, Department of Cell Biology and Developmental, Institute of Biomedical Sciences, University of São Paulo (USP), São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Seelaender+M%22">Seelaender M</searchLink>; Cancer Metabolism Research Group, Department of Surgery, LIM26-HC and C2PO, Faculdade de Medicina, CoMeta-HU, University of São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Lira+FS%22">Lira FS</searchLink>; Exercise and Immunometabolism Research Group, Postgraduation Program in Movement Sciences, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, São Paulo, Brazil.; Faculty of Sports Sciences and Physical Education, CIPER, University of Coimbra, Coimbra, Portugal.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons+Ltd+on+behalf+of+Society+on+Sarcopenia%2C+Cachexia+and+Wasting+Disorders%22">John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101552883 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2190-6009 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221905991%22">21905991 </searchLink><i>NLM ISO Abbreviation: </i>J Cachexia Sarcopenia Muscle <i>Subsets: </i>MEDLINE
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        Value: 10.1002/jcsm.70259
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              M: 04
              Text: 2026 Apr
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              Y: 2026
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