Single-nucleus brain transcriptomics reveals microglia dysfunction in multiple system atrophy.
Saved in:
| Title: | Single-nucleus brain transcriptomics reveals microglia dysfunction in multiple system atrophy. |
|---|---|
| Authors: | Rydbirk R; Functional Genomics and Metabolism Research Unit, Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark.; Center for Neuroscience and Stereology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark., Sørensen FNF; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark., Folke J; Center for Neuroscience and Stereology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark., Haukedal H; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark., Martinez AA; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark., Vargas IL; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark., McGarry S; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark., Hollmann OC; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark., Gherardelli C; Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, USA., Sepulveda S; Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, USA., Szafran AT; Department of Molecular Biology, Baylor College of Medicine, Houston, TX, USA., Mancini MA; Department of Molecular Biology, Baylor College of Medicine, Houston, TX, USA., Kaalund SS; Center for Neuroscience and Stereology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark., Brudek T; Center for Neuroscience and Stereology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark., Salvesen L; Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark., Bech S; Department of Neurology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark., Okarmus J; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark., Kharchenko P; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Meyer M; Department of Neurobiology Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.; Department of Neurology, Odense University Hospital, Odense, Denmark.; Brain Research Inter-Disciplinary Guided Excellence, Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Soto C; Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, USA., Freude K; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg, Denmark., Mukherjee A; Mitchell Center for Alzheimer's Disease and Related Brain Disorders, Department of Neurology, University of Texas Health Science Center at Houston, McGovern Medical School, Houston, USA., Aznar S; Center for Neuroscience and Stereology, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark. Susana.aznar.kleijn@regionh.dk.; Copenhagen Center for Translational Research, Bispebjerg and Frederiksberg Hospital, Copenhagen University Hospital, Copenhagen NV, Denmark. Susana.aznar.kleijn@regionh.dk., Khodosevich K; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen N, Denmark. konstantin.khodosevich@bric.ku.dk. |
| Source: | Nature communications [Nat Commun] 2026 Apr 15; Vol. 17 (1). Date of Electronic Publication: 2026 Apr 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
Be the first to leave a comment!
