Deep single-cell decoding of human pancreatic islets reveals T2D β-cell gene expression defects.
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| Title: | Deep single-cell decoding of human pancreatic islets reveals T2D β-cell gene expression defects. |
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| Authors: | Bandesh K; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Motakis E; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Nargund S; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Kursawe R; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Selvam V; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Ansarullah; The Jackson Laboratory, Center for Biometric Analysis (CBA), Bar Harbor, ME, USA., Bhuiyan RM; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA., Eryilmaz GN; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Willett AM; The Jackson Laboratory, Center for Biometric Analysis (CBA), Bar Harbor, ME, USA., White JK; The Jackson Laboratory, Center for Biometric Analysis (CBA), Bar Harbor, ME, USA., Krishnan SN; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA., Spracklen CN; Department of Biostatistics and Epidemiology, University of Massachusetts Amherst, Amherst, MA, USA., Ucar D; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA.; Institute for Systems Genomics, UConn, Farmington, CT, USA., Stitzel ML; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. michael.stitzel@jax.org.; Department of Genetics and Genome Sciences, UConn Health, Farmington, CT, USA. michael.stitzel@jax.org.; Institute for Systems Genomics, UConn, Farmington, CT, USA. michael.stitzel@jax.org. |
| Source: | The EMBO journal [EMBO J] 2026 Jun; Vol. 45 (11), pp. 3978-4005. Date of Electronic Publication: 2026 Apr 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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