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Loss of schizophrenia risk gene XPO7 disrupts neuronal excitability and network regularity via altered Na+ channel dynamics in human neurons.

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Title: Loss of schizophrenia risk gene XPO7 disrupts neuronal excitability and network regularity via altered Na+ channel dynamics in human neurons.
Authors: Cui L; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA., Kurganov E; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA., Hawes D; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA., Hornauer P; Department of Biosystems Science and Engineering, ETH Zürich, 4056, Basel, Switzerland., Lin R; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA., Wang Y; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA., Hierlemann A; Department of Biosystems Science and Engineering, ETH Zürich, 4056, Basel, Switzerland., Sheng M; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA., Nehme R; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA., Pan JQ; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA. jpan@broadinstitute.org.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Apr 15. Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Loss of schizophrenia risk gene XPO7 disrupts neuronal excitability and network regularity via altered Na<superscript>+</superscript> channel dynamics in human neurons.
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  Data: <searchLink fieldCode="AU" term="%22Cui+L%22">Cui L</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Kurganov+E%22">Kurganov E</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Hawes+D%22">Hawes D</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Hornauer+P%22">Hornauer P</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, 4056, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lin+R%22">Lin R</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Hierlemann+A%22">Hierlemann A</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, 4056, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sheng+M%22">Sheng M</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Nehme+R%22">Nehme R</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Pan+JQ%22">Pan JQ</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, 75 Ames Street, Cambridge, MA 02115, USA. jpan@broadinstitute.org.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2026 Apr 15. <i>Date of Electronic Publication: </i>2026 Apr 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+Specialist+Journals%22">Nature Publishing Group Specialist Journals </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9607835 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5578 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213594184%22">13594184 </searchLink><i>NLM ISO Abbreviation: </i>Mol Psychiatry <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41380-026-03587-3
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              Text: 2026 Apr 15
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