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Real-world effectiveness of highly purified cannabidiol in epilepsy associated with 15q11.2-q13.1 duplication and deletion syndromes: A multicenter study.

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Title: Real-world effectiveness of highly purified cannabidiol in epilepsy associated with 15q11.2-q13.1 duplication and deletion syndromes: A multicenter study.
Authors: Cerulli Irelli E; Department of Human Neurosciences, Sapienza University, Rome, Italy., Mazzeo A; Department of Human Neurosciences, Sapienza University, Rome, Italy., Perulli M; Pediatric Neurology and Psychiatric Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy., Ramantani G; Department of Pediatric Neurology, University Children's Hospital and University of Zurich, Zurich, Switzerland., Battaglia D; Pediatric Neurology and Psychiatric Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.; Department of Health Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy., Bagnasco I; Child Neuropsychiatry Unit, Epilepsy Center for Children, Martini Hospital, Turin, Italy., Cognolato E; Child Neuropsychiatry Unit, Epilepsy Center for Children, Martini Hospital, Turin, Italy., Striano P; Pediatric and Neuromuscular Diseases Unit, Member of the European Reference Network (ERN) for Rare and Complex Epilepsies (EpiCARE), IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy., Negrin S; Scientific Institute IRCCS E.Medea, Epilepsy and Clinical Neurophysiology Unit, Conegliano, Italy., Danieli A; Scientific Institute IRCCS E.Medea, Epilepsy and Clinical Neurophysiology Unit, Conegliano, Italy., Bonanni P; Scientific Institute IRCCS E.Medea, Epilepsy and Clinical Neurophysiology Unit, Conegliano, Italy., Operto FF; Department of Science of Health, School of Medicine, University of Catanzaro, Catanzaro, Italy., Di Bonaventura C; Department of Human Neurosciences, Sapienza University, Rome, Italy., Coppola A; Epilepsy Centre, University Hospital Federico II, Naples, Italy., Orsini A; Pediatric Neurology, University Hospital of Pisa, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
Source: Epilepsia open [Epilepsia Open] 2026 Jun; Vol. 11 (3), pp. 1046-1053. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101692036 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2470-9239 (Electronic) Linking ISSN: 24709239 NLM ISO Abbreviation: Epilepsia Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Real-world effectiveness of highly purified cannabidiol in epilepsy associated with 15q11.2-q13.1 duplication and deletion syndromes: A multicenter study.
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  Data: <searchLink fieldCode="AU" term="%22Cerulli+Irelli+E%22">Cerulli Irelli E</searchLink>; Department of Human Neurosciences, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzeo+A%22">Mazzeo A</searchLink>; Department of Human Neurosciences, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Perulli+M%22">Perulli M</searchLink>; Pediatric Neurology and Psychiatric Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ramantani+G%22">Ramantani G</searchLink>; Department of Pediatric Neurology, University Children's Hospital and University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Battaglia+D%22">Battaglia D</searchLink>; Pediatric Neurology and Psychiatric Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.; Department of Health Science and Public Health, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bagnasco+I%22">Bagnasco I</searchLink>; Child Neuropsychiatry Unit, Epilepsy Center for Children, Martini Hospital, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Cognolato+E%22">Cognolato E</searchLink>; Child Neuropsychiatry Unit, Epilepsy Center for Children, Martini Hospital, Turin, Italy.<br /><searchLink fieldCode="AU" term="%22Striano+P%22">Striano P</searchLink>; Pediatric and Neuromuscular Diseases Unit, Member of the European Reference Network (ERN) for Rare and Complex Epilepsies (EpiCARE), IRCCS Istituto Giannina Gaslini, Genoa, Italy.; Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Negrin+S%22">Negrin S</searchLink>; Scientific Institute IRCCS E.Medea, Epilepsy and Clinical Neurophysiology Unit, Conegliano, Italy.<br /><searchLink fieldCode="AU" term="%22Danieli+A%22">Danieli A</searchLink>; Scientific Institute IRCCS E.Medea, Epilepsy and Clinical Neurophysiology Unit, Conegliano, Italy.<br /><searchLink fieldCode="AU" term="%22Bonanni+P%22">Bonanni P</searchLink>; Scientific Institute IRCCS E.Medea, Epilepsy and Clinical Neurophysiology Unit, Conegliano, Italy.<br /><searchLink fieldCode="AU" term="%22Operto+FF%22">Operto FF</searchLink>; Department of Science of Health, School of Medicine, University of Catanzaro, Catanzaro, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Bonaventura+C%22">Di Bonaventura C</searchLink>; Department of Human Neurosciences, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Coppola+A%22">Coppola A</searchLink>; Epilepsy Centre, University Hospital Federico II, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Orsini+A%22">Orsini A</searchLink>; Pediatric Neurology, University Hospital of Pisa, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101692036%22">Epilepsia open</searchLink> [Epilepsia Open] 2026 Jun; Vol. 11 (3), pp. 1046-1053. <i>Date of Electronic Publication: </i>2026 Apr 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Inc%22">John Wiley & Sons, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101692036 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2470-9239 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224709239%22">24709239 </searchLink><i>NLM ISO Abbreviation: </i>Epilepsia Open <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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