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The Common Fund Data Ecosystem (CFDE).

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Title: The Common Fund Data Ecosystem (CFDE).
Authors: Jurgens JA; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Lead contact., Bueckle A; Department of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA., Vora J; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA., Maurya MR; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA., Ahooyi TM; Department of Biomedical and Health Informatics (DBHi), the Children's Hospital of Philadelphia, Philadelphia, PA, USA., Zheng E; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA., Stear B; Department of Biomedical and Health Informatics (DBHi), the Children's Hospital of Philadelphia, Philadelphia, PA, USA., Wang D; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA., Ree C; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA., Ramachandran S; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA., Nekrutenko A; Huck Institutes for Life Sciences, Penn State University, University Park, PA, USA., Brandes M; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Thaker S; Systems Pharmacology AI Research Center, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA., Katz DH; Division of Computational Medicine, Stanford University, Stanford, CA, USA; Division of Cardiovascular Medicine, Stanford University, CA, USA., Munoz-Torres MC; Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA., Diamant I; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chun HE; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Simmons JA; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Tasian SK; Department of Pediatrics and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA, USA; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Jenkins SL; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Evangelista JE; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dodia H; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA., Saha S; Velsera, Charlestown, MA, USA., Lindquist MA; Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA., Gajjala V; Texas Advanced Computing Center, University of Texas at Austin, Austin, TX, USA., Nemarich C; Center for Data-Driven Discovery in Biomedicine (D3B), the Children's Hospital of Philadelphia, Philadelphia, PA, USA., Zhen J; Department of Medicine, Stanford University, Stanford, CA, USA., Ross KE; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, USA., Byrd AI; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Shilin A; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Metzger VT; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA., Bologa CG; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA., Srinivasan S; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA., Jang D; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kumar P; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA., Taub LD; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Levanto MP; Department of Medicine, Stanford University, Stanford, CA, USA., Petrosyan V; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Anandakrishnan M; Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA., Kim M; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA., Clarke DJB; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ivich A; Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.; Colorado Center for Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Crichton DJ; Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, USA., Smallen S; San Diego Supercomputing Center, The University of California San Diego, La Jolla, CA, USA., Bordelon D; Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, USA., Chen C; Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA., Schroeder AJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Mahabal A; California Institute of Technology, Pasadena, CA, USA., Cao-Berg I; Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, USA., Kim S; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA., Masood D; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA., Yu K; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Gaulton KJ; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA., Jimenez-Morales D; Department of Medicine, Stanford University, Stanford, CA, USA., Rincon JM; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA., Honick BJ; Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, USA., Wang W; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA., Wu CH; Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA., Milosavljevic A; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Blood PD; Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, USA., Boline J; Informed Minds Inc., Walnut Creek, CA, USA., Oprea TI; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA., Lambert CG; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA., de Bono B; Indiana University School of Medicine, Indianapolis, IN, USA; Auckland Bioengineering Institute, Auckland, NZ., Park PJ; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Silverstein JC; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Flannick J; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Yang JJ; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA., Grethe JS; Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, CA, USA., Subramaniam S; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA., Tiemeyer M; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA., Clark T; Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Wheeler MT; Department of Medicine, Stanford University, Stanford, CA, USA., Kahn A; Texas Advanced Computing Center, University of Texas at Austin, Austin, TX, USA., Burnette J; Oak Ridge Associated Universities (ORAU) Government Services, ORAU, Oak Ridge, TN, USA., Ranzinger R; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA., Schatz MC; Departments of Computer Science and Biology, Johns Hopkins University, Baltimore, MD, USA., Gibson L; Oak Ridge Associated Universities (ORAU) Government Services, ORAU, Oak Ridge, TN, USA., Burtt NP; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Carson JP; Texas Advanced Computing Center, University of Texas at Austin, Austin, TX, USA., Chen JY; Systems Pharmacology AI Research Center, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA., Ping P; Department of Biomedical Informatics, College of Medicine at Phoenix, University of Arizona, Phoenix, AZ, USA., Davis S; Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA., Taylor DM; Department of Biomedical and Health Informatics (DBHi), the Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Börner K; Department of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA., Dillman A; BioData Sage, LLC, Bethesda, MD, USA., Bursey K; Oak Ridge Associated Universities (ORAU) Government Services, ORAU, Oak Ridge, TN, USA., Ma'ayan A; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mazumder R; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA.; Senior author., Roth ME; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Senior author., Greene CS; Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.; Colorado Center for Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Senior author.
Corporate Authors: CFDE Consortium
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Apr 16. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41993383
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: The Common Fund Data Ecosystem (CFDE).
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  Data: <searchLink fieldCode="AU" term="%22Jurgens+JA%22">Jurgens JA</searchLink>; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Lead contact.<br /><searchLink fieldCode="AU" term="%22Bueckle+A%22">Bueckle A</searchLink>; Department of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.<br /><searchLink fieldCode="AU" term="%22Vora+J%22">Vora J</searchLink>; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Maurya+MR%22">Maurya MR</searchLink>; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ahooyi+TM%22">Ahooyi TM</searchLink>; Department of Biomedical and Health Informatics (DBHi), the Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+E%22">Zheng E</searchLink>; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Stear+B%22">Stear B</searchLink>; Department of Biomedical and Health Informatics (DBHi), the Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+D%22">Wang D</searchLink>; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ree+C%22">Ree C</searchLink>; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ramachandran+S%22">Ramachandran S</searchLink>; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nekrutenko+A%22">Nekrutenko A</searchLink>; Huck Institutes for Life Sciences, Penn State University, University Park, PA, USA.<br /><searchLink fieldCode="AU" term="%22Brandes+M%22">Brandes M</searchLink>; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Thaker+S%22">Thaker S</searchLink>; Systems Pharmacology AI Research Center, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Katz+DH%22">Katz DH</searchLink>; Division of Computational Medicine, Stanford University, Stanford, CA, USA; Division of Cardiovascular Medicine, Stanford University, CA, USA.<br /><searchLink fieldCode="AU" term="%22Munoz-Torres+MC%22">Munoz-Torres MC</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Diamant+I%22">Diamant I</searchLink>; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chun+HE%22">Chun HE</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Simmons+JA%22">Simmons JA</searchLink>; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Tasian+SK%22">Tasian SK</searchLink>; Department of Pediatrics and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, PA, USA; Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Jenkins+SL%22">Jenkins SL</searchLink>; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Evangelista+JE%22">Evangelista JE</searchLink>; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dodia+H%22">Dodia H</searchLink>; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Saha+S%22">Saha S</searchLink>; Velsera, Charlestown, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lindquist+MA%22">Lindquist MA</searchLink>; Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gajjala+V%22">Gajjala V</searchLink>; Texas Advanced Computing Center, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Nemarich+C%22">Nemarich C</searchLink>; Center for Data-Driven Discovery in Biomedicine (D3B), the Children's Hospital of Philadelphia, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Zhen+J%22">Zhen J</searchLink>; Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ross+KE%22">Ross KE</searchLink>; Department of Biochemistry and Molecular & Cellular Biology, Georgetown University Medical Center, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Byrd+AI%22">Byrd AI</searchLink>; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Shilin+A%22">Shilin A</searchLink>; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Metzger+VT%22">Metzger VT</searchLink>; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22Bologa+CG%22">Bologa CG</searchLink>; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22Srinivasan+S%22">Srinivasan S</searchLink>; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jang+D%22">Jang D</searchLink>; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+P%22">Kumar P</searchLink>; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22Taub+LD%22">Taub LD</searchLink>; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Levanto+MP%22">Levanto MP</searchLink>; Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Petrosyan+V%22">Petrosyan V</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Anandakrishnan+M%22">Anandakrishnan M</searchLink>; Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA.<br /><searchLink fieldCode="AU" term="%22Kim+M%22">Kim M</searchLink>; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Clarke+DJB%22">Clarke DJB</searchLink>; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ivich+A%22">Ivich A</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.; Colorado Center for Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Crichton+DJ%22">Crichton DJ</searchLink>; Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Smallen+S%22">Smallen S</searchLink>; San Diego Supercomputing Center, The University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bordelon+D%22">Bordelon D</searchLink>; Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA.<br /><searchLink fieldCode="AU" term="%22Schroeder+AJ%22">Schroeder AJ</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Mahabal+A%22">Mahabal A</searchLink>; California Institute of Technology, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Cao-Berg+I%22">Cao-Berg I</searchLink>; Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kim+S%22">Kim S</searchLink>; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Masood+D%22">Masood D</searchLink>; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Yu+K%22">Yu K</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Gaulton+KJ%22">Gaulton KJ</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jimenez-Morales+D%22">Jimenez-Morales D</searchLink>; Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rincon+JM%22">Rincon JM</searchLink>; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Honick+BJ%22">Honick BJ</searchLink>; Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wang+W%22">Wang W</searchLink>; Department of Physiology, UCLA School of Medicine, Los Angeles, CA, USA; Scalable Analytics Institute (ScAi) at Department of Computer Science, UCLA School of Engineering, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wu+CH%22">Wu CH</searchLink>; Center for Bioinformatics and Computational Biology, University of Delaware, Newark, DE, USA.<br /><searchLink fieldCode="AU" term="%22Milosavljevic+A%22">Milosavljevic A</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Blood+PD%22">Blood PD</searchLink>; Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Boline+J%22">Boline J</searchLink>; Informed Minds Inc., Walnut Creek, CA, USA.<br /><searchLink fieldCode="AU" term="%22Oprea+TI%22">Oprea TI</searchLink>; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22Lambert+CG%22">Lambert CG</searchLink>; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22de+Bono+B%22">de Bono B</searchLink>; Indiana University School of Medicine, Indianapolis, IN, USA; Auckland Bioengineering Institute, Auckland, NZ.<br /><searchLink fieldCode="AU" term="%22Park+PJ%22">Park PJ</searchLink>; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Silverstein+JC%22">Silverstein JC</searchLink>; Department of Biomedical Informatics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Flannick+J%22">Flannick J</searchLink>; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Yang+JJ%22">Yang JJ</searchLink>; Department of Internal Medicine, University of New Mexico, Albuquerque, NM, USA.<br /><searchLink fieldCode="AU" term="%22Grethe+JS%22">Grethe JS</searchLink>; Department of Neurosciences, School of Medicine, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Subramaniam+S%22">Subramaniam S</searchLink>; Department of Bioengineering, University of California San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tiemeyer+M%22">Tiemeyer M</searchLink>; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.<br /><searchLink fieldCode="AU" term="%22Clark+T%22">Clark T</searchLink>; Department of Public Health Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Wheeler+MT%22">Wheeler MT</searchLink>; Department of Medicine, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kahn+A%22">Kahn A</searchLink>; Texas Advanced Computing Center, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Burnette+J%22">Burnette J</searchLink>; Oak Ridge Associated Universities (ORAU) Government Services, ORAU, Oak Ridge, TN, USA.<br /><searchLink fieldCode="AU" term="%22Ranzinger+R%22">Ranzinger R</searchLink>; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, USA.<br /><searchLink fieldCode="AU" term="%22Schatz+MC%22">Schatz MC</searchLink>; Departments of Computer Science and Biology, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gibson+L%22">Gibson L</searchLink>; Oak Ridge Associated Universities (ORAU) Government Services, ORAU, Oak Ridge, TN, USA.<br /><searchLink fieldCode="AU" term="%22Burtt+NP%22">Burtt NP</searchLink>; Programs in Metabolism and Medical & Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Carson+JP%22">Carson JP</searchLink>; Texas Advanced Computing Center, University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chen+JY%22">Chen JY</searchLink>; Systems Pharmacology AI Research Center, School of Medicine, The University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Ping+P%22">Ping P</searchLink>; Department of Biomedical Informatics, College of Medicine at Phoenix, University of Arizona, Phoenix, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Davis+S%22">Davis S</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+DM%22">Taylor DM</searchLink>; Department of Biomedical and Health Informatics (DBHi), the Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Börner+K%22">Börner K</searchLink>; Department of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA.<br /><searchLink fieldCode="AU" term="%22Dillman+A%22">Dillman A</searchLink>; BioData Sage, LLC, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Bursey+K%22">Bursey K</searchLink>; Oak Ridge Associated Universities (ORAU) Government Services, ORAU, Oak Ridge, TN, USA.<br /><searchLink fieldCode="AU" term="%22Ma'ayan+A%22">Ma'ayan A</searchLink>; Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mazumder+R%22">Mazumder R</searchLink>; Department of Biochemistry and Molecular Medicine, The George Washington University, Washington, DC, USA.; Senior author.<br /><searchLink fieldCode="AU" term="%22Roth+ME%22">Roth ME</searchLink>; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.; Senior author.<br /><searchLink fieldCode="AU" term="%22Greene+CS%22">Greene CS</searchLink>; Department of Biomedical Informatics, University of Colorado Anschutz School of Medicine, Aurora, CO, USA.; Colorado Center for Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.; Senior author.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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            – D: 16
              M: 04
              Text: 2026 Apr 16
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
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            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
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