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A dual-adjuvanted HA stem nanoparticle vaccine elicits a multifunctional antibody response that is associated with protection in newborn monkeys.

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Title: A dual-adjuvanted HA stem nanoparticle vaccine elicits a multifunctional antibody response that is associated with protection in newborn monkeys.
Authors: Crofts KF; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA., Holbrook BC; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA., Page CL; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA., Hendrix CJ; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA., Caudell D; Department of Internal Medicine Section on Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Gillespie RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., D'Agostino RB Jr; Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA., Moin SM; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Sangesland M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Ornelles DA; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA., Kanekiyo M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Alexander-Miller MA; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA. Electronic address: martha.alexander-miller@wfusm.edu.
Source: Cell reports. Medicine [Cell Rep Med] 2026 May 19; Vol. 7 (5), pp. 102746. Date of Electronic Publication: 2026 Apr 16.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
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  Data: A dual-adjuvanted HA stem nanoparticle vaccine elicits a multifunctional antibody response that is associated with protection in newborn monkeys.
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  Data: <searchLink fieldCode="AU" term="%22Crofts+KF%22">Crofts KF</searchLink>; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.<br /><searchLink fieldCode="AU" term="%22Holbrook+BC%22">Holbrook BC</searchLink>; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.<br /><searchLink fieldCode="AU" term="%22Page+CL%22">Page CL</searchLink>; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.<br /><searchLink fieldCode="AU" term="%22Hendrix+CJ%22">Hendrix CJ</searchLink>; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.<br /><searchLink fieldCode="AU" term="%22Caudell+D%22">Caudell D</searchLink>; Department of Internal Medicine Section on Comparative Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Gillespie+RA%22">Gillespie RA</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22D'Agostino+RB+Jr%22">D'Agostino RB Jr</searchLink>; Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.<br /><searchLink fieldCode="AU" term="%22Moin+SM%22">Moin SM</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Sangesland+M%22">Sangesland M</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Ornelles+DA%22">Ornelles DA</searchLink>; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA.<br /><searchLink fieldCode="AU" term="%22Kanekiyo+M%22">Kanekiyo M</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Alexander-Miller+MA%22">Alexander-Miller MA</searchLink>; Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101, USA. Electronic address: martha.alexander-miller@wfusm.edu.
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  Data: <searchLink fieldCode="JN" term="%22101766894%22">Cell reports. Medicine</searchLink> [Cell Rep Med] 2026 May 19; Vol. 7 (5), pp. 102746. <i>Date of Electronic Publication: </i>2026 Apr 16.
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