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Redox rhythms promote fitness by modulating ageing-dependent reprogramming.

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Title: Redox rhythms promote fitness by modulating ageing-dependent reprogramming.
Authors: Wang X; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Cui SS; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Li XK; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Qu SY; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Chang WW; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Tang A; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Jin Y; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Peng SJ; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Wang HP; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Fang XQ; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Lu LY; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Lv CX; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Yu X; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Peng JY; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Wang SS; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China., Wei ZY; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Zhu YT; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Wang HY; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Fu JQ; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Li WQ; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Jin YY; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Chen HZ; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. chenhouzao@ibms.cams.cn., Pei JF; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China. jamffypei@163.com., Liu DP; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. liudp@pumc.edu.cn.
Source: Nature metabolism [Nat Metab] 2026 May; Vol. 8 (5), pp. 1067-1085. Date of Electronic Publication: 2026 Apr 17.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Cui+SS%22">Cui SS</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Li+XK%22">Li XK</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Qu+SY%22">Qu SY</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Chang+WW%22">Chang WW</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Tang+A%22">Tang A</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Jin+Y%22">Jin Y</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Peng+SJ%22">Peng SJ</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+HP%22">Wang HP</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Fang+XQ%22">Fang XQ</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Lu+LY%22">Lu LY</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Lv+CX%22">Lv CX</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Peng+JY%22">Peng JY</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Wang+SS%22">Wang SS</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China.<br /><searchLink fieldCode="AU" term="%22Wei+ZY%22">Wei ZY</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+YT%22">Zhu YT</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wang+HY%22">Wang HY</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Fu+JQ%22">Fu JQ</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+WQ%22">Li WQ</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Jin+YY%22">Jin YY</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+HZ%22">Chen HZ</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. chenhouzao@ibms.cams.cn.<br /><searchLink fieldCode="AU" term="%22Pei+JF%22">Pei JF</searchLink>; Department of Medical Genetics, Key Laboratory of Cell Biology, Ministry of Public Health, and Key Laboratory of Medical Cell Biology, Ministry of Education, Key Laboratory of Advanced Reproductive Medicine and Fertility, NHC Key Laboratory of Advanced Reproductive Medicine and Fertility, National Health Commission, China Medical University, Shenyang, China. jamffypei@163.com.<br /><searchLink fieldCode="AU" term="%22Liu+DP%22">Liu DP</searchLink>; State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences & School of Basic Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. liudp@pumc.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101736592%22">Nature metabolism</searchLink> [Nat Metab] 2026 May; Vol. 8 (5), pp. 1067-1085. <i>Date of Electronic Publication: </i>2026 Apr 17.
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