Combined elevation of pre-treatment γ-glutamyltransferase and lactate dehydrogenase as independent prognosticator for metastatic renal cell carcinoma undergoing immune-based therapy.

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Title: Combined elevation of pre-treatment γ-glutamyltransferase and lactate dehydrogenase as independent prognosticator for metastatic renal cell carcinoma undergoing immune-based therapy.
Authors: Uhlig A; Department of Urology, University Hospital Tübingen, Tübingen, Germany., Mattigk A; Department of Urology and Paediatric Urology, University Hospital Ulm, Ulm, Germany., Sondermann M; Department of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Hoeh B; Department of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Cano Garcia C; Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, Frankfurt, Germany., Klümper N; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany.; Department of Urology, University Hospital Bonn, Bonn, Germany., Cox A; Department of Urology, University Hospital Bonn, Bonn, Germany., Hahn O; Department of Urology and Paediatric Urology, Julius Maximilians University Medical Center of Würzburg, Würzburg, Germany., Schmucker P; Department of Urology, University Hospital Freiburg, Freiburg, Germany., Flegar L; Department of Urology, Philipps-University Marburg, Marburg, Germany., Vollemaere J; Department of Urology and Paediatric Urology, Saarland University, Homburg/Saar, Germany., Zengerling F; Department of Urology and Paediatric Urology, University Hospital Ulm, Ulm, Germany., Banek S; Department of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, Frankfurt, Germany., Ellinger J; Department of Urology, University Hospital Bonn, Bonn, Germany., Huber J; Department of Urology, Philipps-University Marburg, Marburg, Germany., Zeuschner P; Department of Urology and Paediatric Urology, Saarland University, Homburg/Saar, Germany., Kalogirou C; Department of Urology and Paediatric Urology, Julius Maximilians University Medical Center of Würzburg, Würzburg, Germany., Erdmann K; Department of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. kati.erdmann@ukdd.de.
Corporate Authors: German Society of Residents in Urology (GeSRU) Academics Renal Cell Carcinoma Work Group
Source: Scientific reports [Sci Rep] 2026 Apr 18; Vol. 16 (1). Date of Electronic Publication: 2026 Apr 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Combined elevation of pre-treatment γ-glutamyltransferase and lactate dehydrogenase as independent prognosticator for metastatic renal cell carcinoma undergoing immune-based therapy.
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  Data: <searchLink fieldCode="AU" term="%22Uhlig+A%22">Uhlig A</searchLink>; Department of Urology, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Mattigk+A%22">Mattigk A</searchLink>; Department of Urology and Paediatric Urology, University Hospital Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Sondermann+M%22">Sondermann M</searchLink>; Department of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Hoeh+B%22">Hoeh B</searchLink>; Department of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Cano+Garcia+C%22">Cano Garcia C</searchLink>; Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Klümper+N%22">Klümper N</searchLink>; Institute of Experimental Oncology, University Hospital Bonn, Bonn, Germany.; Department of Urology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Cox+A%22">Cox A</searchLink>; Department of Urology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Hahn+O%22">Hahn O</searchLink>; Department of Urology and Paediatric Urology, Julius Maximilians University Medical Center of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schmucker+P%22">Schmucker P</searchLink>; Department of Urology, University Hospital Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Flegar+L%22">Flegar L</searchLink>; Department of Urology, Philipps-University Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Vollemaere+J%22">Vollemaere J</searchLink>; Department of Urology and Paediatric Urology, Saarland University, Homburg/Saar, Germany.<br /><searchLink fieldCode="AU" term="%22Zengerling+F%22">Zengerling F</searchLink>; Department of Urology and Paediatric Urology, University Hospital Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Banek+S%22">Banek S</searchLink>; Department of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.; Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Ellinger+J%22">Ellinger J</searchLink>; Department of Urology, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Huber+J%22">Huber J</searchLink>; Department of Urology, Philipps-University Marburg, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Zeuschner+P%22">Zeuschner P</searchLink>; Department of Urology and Paediatric Urology, Saarland University, Homburg/Saar, Germany.<br /><searchLink fieldCode="AU" term="%22Kalogirou+C%22">Kalogirou C</searchLink>; Department of Urology and Paediatric Urology, Julius Maximilians University Medical Center of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Erdmann+K%22">Erdmann K</searchLink>; Department of Urology, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. kati.erdmann@ukdd.de.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Apr 18; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Apr 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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