Targeting ATP11B-YAP axis repairs mitochondrial function and inhibits neuronal ferroptosis to attenuate age-related cognitive decline.
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| Title: | Targeting ATP11B-YAP axis repairs mitochondrial function and inhibits neuronal ferroptosis to attenuate age-related cognitive decline. |
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| Authors: | Qi W; School of Life Sciences, Shanghai University, Shanghai, China.; Shanghai Institute of Nutrition and Health, Chinese Academy of Science, Shanghai, China., Liu Q; School of Life Sciences, Shanghai University, Shanghai, China., Dong N; School of Life Sciences, Shanghai University, Shanghai, China.; Jinan Microecological Biomedicine Shandong Laboratory, Jinan, China., Sun X; Cancer Institute/Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shangh, China., Wu P; School of Life Sciences, Shanghai University, Shanghai, China., Zhou J; School of Life Sciences, Shanghai University, Shanghai, China., Sun R; School of Life Sciences, Shanghai University, Shanghai, China., Liu Y; Department of General Surgery, Pancreatic Disease Center, Research Institute of Pancreatic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. xb88053@sjtu.edu.cn., Zhao RC; School of Life Sciences, Shanghai University, Shanghai, China. zhaochunhua@vip.163.com.; Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China. zhaochunhua@vip.163.com.; Centre of Excellence in Tissue Engineering, Chinese Academy of Medical Sciences, Beijing, China. zhaochunhua@vip.163.com.; Beijing Key Laboratory of New Drug Development and Clinical Trial of Stem Cell Therapy, Beijing, China. zhaochunhua@vip.163.com., Wang J; School of Life Sciences, Shanghai University, Shanghai, China. jo717@shu.edu.cn.; School of Life Science and Technology, Shandong Vocational University of Foreign Affairs, Jinan, China. jo717@shu.edu.cn.; Department of Rehabilitation Medicine, The Affiliated Taian City Central Hospital of Qingdao University, Taian, China. jo717@shu.edu.cn.; Key Laboratory of Biotechnology and Bioengineering of State Ethnic Affairs Commission, Northwest Minzu University, Lanzhou, Gansu, China. jo717@shu.edu.cn. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Apr 20; Vol. 11 (1). Date of Electronic Publication: 2026 Apr 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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