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Reversion to normoglycemia with tirzepatide vs semaglutide in participants with obesity and prediabetes: a post hoc analysis of SURMOUNT-5.

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Title: Reversion to normoglycemia with tirzepatide vs semaglutide in participants with obesity and prediabetes: a post hoc analysis of SURMOUNT-5.
Authors: Galindo RJ; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA., Aronne LJ; Division of Endocrinology, Diabetes and Metabolism, Weill Cornell Medicine, Comprehensive Weight Control Center, New York, NY, USA., Horn DB; Center for Obesity Medicine and Metabolic Performance, Departments of Internal Medicine and Surgery, University of Texas McGovern Medical School, Houston, TX, USA., Miras AD; School of Medicine, Ulster University, Derry, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, SW7 2AZ, UK., Dunn JP; Eli Lilly and Company, Indianapolis, IN, USA., Cao D; Eli Lilly and Company, Indianapolis, IN, USA., Lee CJ; Eli Lilly and Company, Indianapolis, IN, USA., Karanikas CA; Eli Lilly and Company, Indianapolis, IN, USA., Heine RJ; Eli Lilly and Company, Indianapolis, IN, USA., Falcon BL; Eli Lilly and Company, Indianapolis, IN, USA., Dimitriadis GK; Eli Lilly and Company, Indianapolis, IN, USA. georgios.dimitriadis@lilly.com.; Eli Lilly and Company Ltd., Basingstoke, UK. georgios.dimitriadis@lilly.com.
Source: Journal of endocrinological investigation [J Endocrinol Invest] 2026 Apr 20. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Italy NLM ID: 7806594 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1720-8386 (Electronic) Linking ISSN: 03914097 NLM ISO Abbreviation: J Endocrinol Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Reversion to normoglycemia with tirzepatide vs semaglutide in participants with obesity and prediabetes: a post hoc analysis of SURMOUNT-5.
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  Data: <searchLink fieldCode="AU" term="%22Galindo+RJ%22">Galindo RJ</searchLink>; Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Aronne+LJ%22">Aronne LJ</searchLink>; Division of Endocrinology, Diabetes and Metabolism, Weill Cornell Medicine, Comprehensive Weight Control Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Horn+DB%22">Horn DB</searchLink>; Center for Obesity Medicine and Metabolic Performance, Departments of Internal Medicine and Surgery, University of Texas McGovern Medical School, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Miras+AD%22">Miras AD</searchLink>; School of Medicine, Ulster University, Derry, UK.; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, SW7 2AZ, UK.<br /><searchLink fieldCode="AU" term="%22Dunn+JP%22">Dunn JP</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Cao+D%22">Cao D</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Lee+CJ%22">Lee CJ</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Karanikas+CA%22">Karanikas CA</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Heine+RJ%22">Heine RJ</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Falcon+BL%22">Falcon BL</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Dimitriadis+GK%22">Dimitriadis GK</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA. georgios.dimitriadis@lilly.com.; Eli Lilly and Company Ltd., Basingstoke, UK. georgios.dimitriadis@lilly.com.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Italy <i>NLM ID: </i>7806594 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1720-8386 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203914097%22">03914097 </searchLink><i>NLM ISO Abbreviation: </i>J Endocrinol Invest <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 20
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