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Plasma von Willebrand Factor and ADAMTS13 Interact With APOE-ε4 in Predicting Longitudinal Brain Atrophy and Cognitive Decline Over a 9-Year Follow-Up.

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Title: Plasma von Willebrand Factor and ADAMTS13 Interact With APOE-ε4 in Predicting Longitudinal Brain Atrophy and Cognitive Decline Over a 9-Year Follow-Up.
Authors: Adegboye HA; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Medical Scientist Training Program Vanderbilt University School of Medicine Nashville TN USA.; Vanderbilt Brain Institute Vanderbilt University School of Medicine Nashville TN USA., Sun Y; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA., Zhang P; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA., Liu D; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA., Khan OA; Vanderbilt Brain Institute Vanderbilt University School of Medicine Nashville TN USA.; Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA.; Department of Psychology and Human Development Vanderbilt University Nashville TN USA., Tanriverdi K; Department of Medicine Vanderbilt University Medical Center Nashville TN USA., Risitano A; Department of Medicine Vanderbilt University Medical Center Nashville TN USA., Libby J; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA., Patterson KL; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Chemistry Vanderbilt University Nashville TN USA., Arul AB; Department of Chemistry Vanderbilt University Nashville TN USA., Oliver NC; Department of Chemistry Vanderbilt University Nashville TN USA., Whitaker MD; Department of Medicine Vanderbilt University Medical Center Nashville TN USA., Janve VA; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA., Dumitrescu LC; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Neurology Vanderbilt University Medical Center Nashville TN USA., Pechman KR; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA., Shashikumar N; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA., Bolton CJ; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Medicine Vanderbilt University Medical Center Nashville TN USA., Davis LT; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Neurology Vanderbilt University Medical Center Nashville TN USA.; Department of Radiology Vanderbilt University Medical Center Nashville TN USA., Landman BA; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Electrical and Computer Engineering Vanderbilt University Nashville TN USA., Freedman JE; Department of Medicine Vanderbilt University Medical Center Nashville TN USA., Robinson RAS; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Chemistry Vanderbilt University Nashville TN USA., Hohman TJ; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Neurology Vanderbilt University Medical Center Nashville TN USA., Jefferson AL; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Vanderbilt Brain Institute Vanderbilt University School of Medicine Nashville TN USA.; Department of Medicine Vanderbilt University Medical Center Nashville TN USA.; Department of Neurology Vanderbilt University Medical Center Nashville TN USA.
Source: Journal of the American Heart Association [J Am Heart Assoc] 2026 May 05; Vol. 15 (9), pp. e043186. Date of Electronic Publication: 2026 Apr 20.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
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  Data: Plasma von Willebrand Factor and ADAMTS13 Interact With APOE-ε4 in Predicting Longitudinal Brain Atrophy and Cognitive Decline Over a 9-Year Follow-Up.
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  Data: <searchLink fieldCode="AU" term="%22Adegboye+HA%22">Adegboye HA</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Medical Scientist Training Program Vanderbilt University School of Medicine Nashville TN USA.; Vanderbilt Brain Institute Vanderbilt University School of Medicine Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Zhang+P%22">Zhang P</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Liu+D%22">Liu D</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Khan+OA%22">Khan OA</searchLink>; Vanderbilt Brain Institute Vanderbilt University School of Medicine Nashville TN USA.; Department of Biostatistics Vanderbilt University Medical Center Nashville TN USA.; Department of Psychology and Human Development Vanderbilt University Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Tanriverdi+K%22">Tanriverdi K</searchLink>; Department of Medicine Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Risitano+A%22">Risitano A</searchLink>; Department of Medicine Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Libby+J%22">Libby J</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Patterson+KL%22">Patterson KL</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Chemistry Vanderbilt University Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Arul+AB%22">Arul AB</searchLink>; Department of Chemistry Vanderbilt University Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Oliver+NC%22">Oliver NC</searchLink>; Department of Chemistry Vanderbilt University Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Whitaker+MD%22">Whitaker MD</searchLink>; Department of Medicine Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Janve+VA%22">Janve VA</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Dumitrescu+LC%22">Dumitrescu LC</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Neurology Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Pechman+KR%22">Pechman KR</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Shashikumar+N%22">Shashikumar N</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Bolton+CJ%22">Bolton CJ</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Medicine Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Davis+LT%22">Davis LT</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Neurology Vanderbilt University Medical Center Nashville TN USA.; Department of Radiology Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Landman+BA%22">Landman BA</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Electrical and Computer Engineering Vanderbilt University Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Freedman+JE%22">Freedman JE</searchLink>; Department of Medicine Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Robinson+RAS%22">Robinson RAS</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Chemistry Vanderbilt University Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Hohman+TJ%22">Hohman TJ</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Department of Neurology Vanderbilt University Medical Center Nashville TN USA.<br /><searchLink fieldCode="AU" term="%22Jefferson+AL%22">Jefferson AL</searchLink>; Vanderbilt Memory and Alzheimer's Center Vanderbilt University School of Medicine Nashville TN USA.; Vanderbilt Brain Institute Vanderbilt University School of Medicine Nashville TN USA.; Department of Medicine Vanderbilt University Medical Center Nashville TN USA.; Department of Neurology Vanderbilt University Medical Center Nashville TN USA.
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  Data: <searchLink fieldCode="JN" term="%22101580524%22">Journal of the American Heart Association</searchLink> [J Am Heart Assoc] 2026 May 05; Vol. 15 (9), pp. e043186. <i>Date of Electronic Publication: </i>2026 Apr 20.
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